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Dentin is classified into three types: primary, secondary, and tertiary. [24] [25] Secondary dentin is a layer of dentin formed after the tooth's root has fully formed. Tertiary dentin develops as a result of a stimulus, such as a carious attack or wear. [26]
Reactionary dentin is formed by odontoblasts when the injury does not damage the odontoblast layer. Reparative dentin is formed by replacement odontoblasts when the injury is so severe that it damages a part of the primary odontoblast layer. Thus a type of tertiary dentin forms in reaction to stimuli, such as attrition or dental caries.
Tertiary dentin on the surface of a gorilla tooth. The darker area indicated by the white arrow is tertiary dentin and has formed as a response to tooth wear. Wear on the surface of a tooth can lead to the exposure of the underlying dentin. When wear is severe tertiary dentin may form to help protect the pulp chamber. [4]
Dentin formation, known as dentinogenesis, is the first identifiable feature in the crown stage of tooth development. The formation of dentin must always occur before the formation of enamel. The different stages of dentin formation result in different types of dentin: mantle dentin, primary dentin, secondary dentin, and tertiary dentin. [31]
There are three types of dentin, primary, secondary and tertiary. [19] Secondary dentin is a layer of dentin produced after root formation and continues to form with age. Tertiary dentin is created in response to stimulus, such as cavities and tooth wear. [20]
This new dentin is referred to as tertiary dentin. [82] Tertiary dentin is produced to protect the pulp for as long as possible from the advancing bacteria. As more tertiary dentin is produced, the size of the pulp decreases. This type of dentin has been subdivided according to the presence or absence of the original odontoblasts. [85]
Odontoblasts also secrete tertiary dentin when irritated. Tertiary dentin secreted by odontoblasts is often due to chemical attack, either by chemicals diffusing through the dentin and insulting the odontoblasts, or by diffusion of toxic bacterial metabolites down the dentinal tubules in the instance of a carious attack with dental decay. This ...
The heart derives from embryonic mesodermal germ layer cells that differentiate after gastrulation into mesothelium, endothelium, and myocardium.Heart induction occurs in the anterior mesoderm during gastrulation through interactions with adjacent endoderm (both extra-embryonic and definitive) mediated primarily by endogenous inhibitors of WNT signaling such as DKK1.