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Bronchiectasis may result from congenital disorders that affect cilia motility or ion transport. [51] A common genetic cause is cystic fibrosis, which affects chloride ion transport. [28] Another genetic cause is primary ciliary dyskinesia, a rare disorder that leads to immotility of cilia and can lead to situs inversus. [52]
[4] [5] [6] Due to its rarity it presents a difficulty in adult diagnoses, and its initial presentation can be confused with septic shock. [ 7 ] Diagnosis requires an appropriate clinical history , the characteristic expiratory airway collapse on radiological investigation, and exclusion of other causes of congenital and acquired bronchiectasis .
Obstructive lung disease is a category of respiratory disease characterized by airway obstruction.Many obstructive diseases of the lung result from narrowing (obstruction) of the smaller bronchi and larger bronchioles, often because of excessive contraction of the smooth muscle itself.
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In children, hemoptysis is commonly caused by the presence of a foreign body in the airway. Other common causes include lung cancers and tuberculosis. Less common causes include aspergilloma, bronchiectasis, coccidioidomycosis, pulmonary embolism, pneumonic plague, and cystic fibrosis.
Other causes of similar symptoms include asthma, pneumonia, bronchiolitis, bronchiectasis, and COPD. [2] [4] A chest X-ray may be useful to detect pneumonia. [4] Another common sign of bronchitis is a cough lasting ten days to three weeks. If the cough lasts longer than a month, it may become chronic bronchitis. In addition, a fever may be present.
There is still much debate to whether pulmonary sequestration is a congenital problem or acquired through recurrent pulmonary infection. It is widely believed that extralobar pulmonary sequestrations are a result of prenatal pulmonary malformation while intralobar pulmonary sequestrations can develop due to recurrent pulmonary infections in adolescents and young adults.
About 10% to 30% of children under the age of two years are affected by bronchiolitis at some point in time. [1] [2] It commonly occurs in the winter season in the Northern Hemisphere. [1] It is the leading cause of hospitalizations in those less than one year of age in the United States.