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  2. Gleason grading system - Wikipedia

    en.wikipedia.org/wiki/Gleason_grading_system

    Gleason scores are often grouped together, based on similar behaviour: Grade 2-4 as well-differentiated, Grade 5-6 as intermediately-differentiated, Grade 7 as moderately to poorly differentiated (either 3+4=7, where the majority is pattern 3, or 4+3=7 in which pattern 4 dominates and indicates less differentiation., [6] and Grade 8-10 as "high ...

  3. Prostate cancer staging - Wikipedia

    en.wikipedia.org/wiki/Prostate_cancer_staging

    Of note, this system of describing tumors as "well-", "moderately-", and "poorly-" differentiated based on Gleason score of 24, 5–6, and 7–10, respectively, persists in SEER and other databases but is generally outdated. In recent years pathologists rarely assign a tumor a grade less than 3, particularly in biopsy tissue. [citation needed]

  4. Prostate cancer - Wikipedia

    en.wikipedia.org/wiki/Prostate_cancer

    [note 1] Gleason scores are commonly grouped into "Gleason grade groups", which predict disease prognosis: a Gleason score of 6 is Gleason grade group 1 (best prognosis). A score of 7 (with Gleason scores 4 + 3, or Gleason scores 3 + 4, with the most prominent listed first) can be grade group 2 or 3; it is grade group 2 if the less severe ...

  5. Grading (tumors) - Wikipedia

    en.wikipedia.org/wiki/Grading_(tumors)

    Of the many cancer-specific schemes, the Gleason system, [3] named after Donald Floyd Gleason, used to grade the adenocarcinoma cells in prostate cancer is the most famous. This system uses a grading score ranging from 2 to 10. Lower Gleason scores describe well-differentiated less aggressive tumors.

  6. Prostate biopsy - Wikipedia

    en.wikipedia.org/wiki/Prostate_biopsy

    Prostate biopsy is a procedure in which small hollow needle-core samples are removed from a man's prostate gland to be examined for the presence of prostate cancer.It is typically performed when the result from a PSA blood test is high. [1]

  7. Histopathologic diagnosis of prostate cancer - Wikipedia

    en.wikipedia.org/wiki/Histopathologic_diagnosis...

    0.7 to 2.8% [12] Umbrella cells are usually present in low-grade tumors [13] Frequently branching fibrovascular cores [13] Frequently fusing of papillae [13] Not recommended [1] Small-cell carcinoma 0.32% [14] [15] [notes 1] Small blue cells with scant cytoplasm [1] High nucleus/cytoplasm ratio [1] "salt and pepper" chromatin [1] Nuclear ...

  8. Active surveillance of prostate cancer - Wikipedia

    en.wikipedia.org/wiki/Active_surveillance_of...

    In a separate study of men from the pre prostate cancer screening era managed with watchful waiting (56% over age 70 years), progression to distant metastasis or prostate cancer death was 13.9% and 12.3%, respectively for Gleason score 6 or below, but considerably higher at 18.2 and 22.7%, 30% and 20%, 44.4% and 55.6% for Gleason 3+4, 4+3, and ...

  9. Talk:Gleason grading system - Wikipedia

    en.wikipedia.org/wiki/Talk:Gleason_Grading_System

    The lowest possible Gleason score is 2 (1 + 1), where both the primary and secondary patterns have a Gleason grade of 1 and therefore when added together their combined sum is 2. 2. Very typical Gleason scores might be 5 (2 + 3), where the primary pattern has a Gleason grade of 2 and the secondary pattern has a grade of 3, or 6 (3 + 3), a pure ...

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