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Gallbladder cancer is a relatively uncommon cancer, with an incidence of fewer than 2 cases per 100,000 people per year in the United States. [7] It is particularly common in central and South America, central and eastern Europe, Japan and northern India; it is also common in certain ethnic groups e.g. Native American Indians and Hispanics. [8]
Cholecystectomy is the surgical removal of the gallbladder.Cholecystectomy is a common treatment of symptomatic gallstones and other gallbladder conditions. [1] In 2011, cholecystectomy was the eighth most common operating room procedure performed in hospitals in the United States. [2]
Cancer of the gallbladder may also be found incidentally after surgical removal of the gallbladder, with 1–3% of cancers identified in this way. Gallbladder polyps are mostly benign growths or lesions resembling growths that form in the gallbladder wall, [ 26 ] and are only associated with cancer when they are larger in size (>1 cm). [ 21 ]
Due to the increased risk for gallbladder cancer, the recommended treatment is cholecystectomy which usually includes pre-operative or intra-operative imaging of the biliary tree. Cholecystectomy may be performed via an open incision or via laparoscopic methods, but gallbladder anatomy and consistency may complicate the operation.
In 2008, the Mayo Clinic reported significant success treating early bile duct cancer with liver transplantation using a protocolized approach and strict selection criteria. [ 71 ] Adjuvant therapy followed by liver transplantation may have a role in treatment of certain unresectable cases. [ 72 ]
Treatment of bile leaks: leakage of bile into the abdominal cavity is a complication of laparoscopic cholecystectomy. The purpose of biliary endoscopic sphincterotomy in the treatment of a bile leak is to reduce or eliminate the pressure gradient between the bile duct and the duodenum, encouraging transpapillary bile flow and allowing the leak ...
Other procedures associated with ERCP include the trawling of the common bile duct with a basket or balloon to remove gallstones and the insertion of a plastic stent to assist the drainage of bile. [11] Also, the pancreatic duct can be cannulated and stents be inserted. The pancreatic duct requires visualisation in cases of pancreatitis.
In rare cases when surgery is not possible, medication can be used to dissolve the stones or lithotripsy can be used to break them down. [7] In developed countries, 10–15% of adults experience gallstones. [4] Gallbladder and biliary-related diseases occurred in about 104 million people (1.6% of people) in 2013 and resulted in 106,000 deaths.