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Sirtuin 1, also known as NAD-dependent deacetylase sirtuin-1, is a protein that in humans is encoded by the SIRT1 gene. [5] [6] [7]SIRT1 stands for sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae), referring to the fact that its sirtuin homolog (biological equivalent across species) in yeast (Saccharomyces cerevisiae) is Sir2.
SIRT1 protein promotes homologous recombination in human cells and is involved in recombinational repair of DNA breaks. [ 29 ] SIRT6 is a chromatin -associated protein and in mammalian cells is required for base excision repair of DNA damage . [ 30 ]
UniProt Archive (UniParc) is a comprehensive and non-redundant database, which contains all the protein sequences from the main, publicly available protein sequence databases. [17] Proteins may exist in several different source databases, and in multiple copies in the same database.
Hnyat-phanat. Hnyat-phanat (Burmese: ညှပ်ဖိနပ်; MLCTS: hnyap hpi. nap, IPA: [ɲ̥appʰənaʔ]) is a Burmese traditional sandal, similar to flip-flops. [1] [2] Although it refers to almost any sandal worn by the people of Myanmar, it is mostly used to refer to the traditional Mandalay velvet slippers that originate in Upper Burma ().
Slip-ons are typically low, lace-less shoes. [1] The style which is most commonly seen, known as a loafer , slippers , or penny loafers in American culture, has a moccasin construction. One of the first designs was introduced in London by Wildsmith Shoes , called the Wildsmith Loafer. [ 2 ]
Unlike slippers and mules, which are closed at the front, slide shoes are never closed at the front, they leave the toes visible and in the open air. They can be made with any type of material, from leather to fabric, from natural fibers to synthetic materials. They are mainly used at the beach or at the swimming pool.
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