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A seizure is a sudden change in behavior, movement, and/or consciousness due to abnormal electrical activity in the brain. [3] [6] Seizures can look different in different people.It can be uncontrolled shaking of the whole body (tonic-clonic seizures) or a person spacing out for a few seconds (absence seizures).[3] [12] [8] Most seizures last less than two minutes. [5]
Convulsive status epilepticus (SE) is a common neurological emergency that disproportionately affects young children and older adults [1 – 3]. SE is associated with a mortality of approximately 0–3% in children [1, 4 – 7], 20–30% in older adults [7 – 9], and survivors often have neurological and cognitive deficits.
Seizure causes include almost any type of damage to the brain, including injury and infection. Recurrent seizures are a sign of epilepsy. Seizures generally stop on their own. Because someone having a seizure is unconscious, it is important to help the person avoid self-injury. Following a seizure, the person may be tired and require rest.
A. Vanderver. Medicine. American Journal of Neuroradiology. 2022. TLDR. Imaging phenotypes in germline H3F3-affected individuals are related to brain features, including a small posterior fossa as well as dysgenesis of the corpus callosum, cortical developmental abnormalities, and deformity of lateral ventricles. Expand.
Genetic diagnosis represents progress in the management of paediatric epilepsy, providing a deeper understanding of the condition's underlying causes and opening the door to personalized treatments. Through technologies like Whole Exome Sequencing, clinicians can now accurately diagnose complex cases, optimize treatment plans, and improve ...
Epilepsy and its treatment are complex, and the evidence suggests knowledge of seizure classification is insufficient and there are gaps in epilepsy diagnosis and care. This article provides an overview of the condition, including incidence, classification, aetiology, pathophysiology, clinical manifestations and symptom management.
Decoding Epileptic Seizures: Exploring In Vitro Approaches to Unravel Pathophysiology and Propel Future Therapeutic Breakthroughs. Y. Heydari, Y. Bozzi and L. Pavesi
Time of seizure onset relative to MS diagnosis varied with MS type suggesting distinct pathophysiology. EEG results correspond with reports of increased cortical damage and temporal dysfunction in PPMS, but are unique as a functional modality (EEG) as indicator of gray matter dysfunction. EEG findin …
Zoning out generally describes a mild form of dissociation. Dissociation is a lapse in how your mind normally works, during which you may feel may feel disconnected from your thoughts, feelings, memories, and surroundings. Most lapses are momentary, lasting for seconds or minutes, although some episodes may last longer.
Seizure medicines work in complex ways. Many medicines act on brain cells to affect the way substances move in and out of the cells. Others try to change the way substances called ‘neurotransmitters’ excite (e.g. stimulate) or inhibit (e.g. stop or slow down) the way information is sent from one cell and area of the brain to another.