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In 1959, phentermine first received approval from the United States FDA as an appetite-suppressing drug. [17] Eventually a hydrochloride salt and a resin form became available. [17] Phentermine was marketed with fenfluramine or dexfenfluramine as a combination appetite suppressant and fat burning agent under the popular name fen-phen. [18]
Phentermine is a stimulant and appetite suppressant. [2] Topiramate is an anticonvulsant that has weight loss side effects. [ 2 ] The exact mechanism of action for both drugs is unknown.
Fenfluramine as a single drug was first introduced in the 1970s, but was not popular because it only temporarily reduced weight. [1] A 1984 study found a weight loss of 7.5 kg on average in 24 weeks, as compared to 4.4 kg under placebo. [4] It sold modestly until the 1990s, when it was combined with phentermine and heavily marketed.
Adderall and Mydayis [10] are trade names [note 2] for a combination drug containing four salts of amphetamine.The mixture is composed of equal parts racemic amphetamine and dextroamphetamine, which produces a (3:1) ratio between dextroamphetamine and levoamphetamine, the two enantiomers of amphetamine. [12]
Venlafaxine, sold under the brand name Effexor among others, is an antidepressant medication of the serotonin–norepinephrine reuptake inhibitor (SNRI) class. [6] [9] It is used to treat major depressive disorder, generalized anxiety disorder, panic disorder, and social anxiety disorder. [9]
Borderline personality disorder. Borderline personality disorder (BPD), also known as emotionally unstable personality disorder (EUPD), [16] is a personality disorder characterized by a pervasive, long-term pattern of significant interpersonal relationship instability, a distorted sense of self, and intense emotional responses. [9][17][18 ...
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