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The Institute for Laboratory Animal Research (ILAR) is a United States organization which develops and shares information and guidelines about animal testing and care of laboratory animals. [1] It is a unit in the United States National Research Council. Their mission is "to evaluate and to report on scientific, technological, and ethical use ...
In 1954, the Universities Federation for Animal Welfare (UFAW) decided to sponsor systematic research on the progress of humane techniques in the laboratory. [2] In October of that year, William Russell, described as a brilliant young zoologist who happened to be also a psychologist and a classical scholar, and Rex Burch, a microbiologist, were appointed to inaugurate a systematic study of ...
Docking is the intentional removal of part of an animal's tail or, sometimes, ears. The term cropping is more commonly used in reference to the cropping of ears, while docking more commonly—but not exclusively—refers to the tail; the term tailing is used, also. The term has its origins in the living flesh of the tail, commonly known as the ...
Vesicle (biology and chemistry) Scheme of a liposome formed by phospholipids in an aqueous solution. In cell biology, a vesicle is a structure within or outside a cell, consisting of liquid or cytoplasm enclosed by a lipid bilayer. Vesicles form naturally during the processes of secretion (exocytosis), uptake (endocytosis), and the transport of ...
Cell culture in a special tissue culture dish. Cell culture can be an alternative to animal use in some cases. For example, cultured cells have been developed to create monoclonal antibodies; prior to this, production required animals to undergo a procedure likely to cause pain and distress. [7]
Connexon. In biology, a connexon, also known as a connexin hemichannel, is an assembly of six proteins called connexins that form the pore for a gap junction between the cytoplasm of two adjacent cells. This channel allows for bidirectional flow of ions and signaling molecules. [1] The connexon is the hemichannel supplied by a cell on one side ...
This process of the second bacterial cell taking up new genetic material is called transformation. In molecular biology and genetics, transformation is the genetic alteration of a cell resulting from the direct uptake and incorporation of exogenous genetic material from its surroundings through the cell membrane (s).
Around 50–100 million vertebrate animals are used in experiments annually. Animal testing, also known as animal experimentation, animal research, and in vivo testing, is the use of non-human animals, such as model organisms, in experiments that seek to control the variables that affect the behavior or biological system under study.