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  2. DNA synthesis - Wikipedia

    en.wikipedia.org/wiki/DNA_synthesis

    DNA replication also works by using a DNA template, the DNA double helix unwinds during replication, exposing unpaired bases for new nucleotides to hydrogen bond to. Gene synthesis, however, does not require a DNA template and genes are assembled de novo. DNA synthesis occurs in all eukaryotes and prokaryotes, as well as some viruses. The ...

  3. Biosynthesis - Wikipedia

    en.wikipedia.org/wiki/Biosynthesis

    Biosynthesis, i.e., chemical synthesis occurring in biological contexts, is a term most often referring to multi-step, enzyme-catalyzed processes where chemical substances absorbed as nutrients (or previously converted through biosynthesis) serve as enzyme substrates, with conversion by the living organism either into simpler or more complex ...

  4. Thymidylate synthase - Wikipedia

    en.wikipedia.org/wiki/Thymidylate_synthase

    Thymidylate synthase (TS) plays a crucial role in the early stages of DNA biosynthesis. [11] DNA damage or deletion occur on a daily basis as a result of both endogenous and environmental factors. Such environmental factors include ultraviolet damage and cigarette smoke that contain a variety of carcinogens. [12] Therefore, synthesis and ...

  5. Nucleic acid metabolism - Wikipedia

    en.wikipedia.org/wiki/Nucleic_acid_metabolism

    Nucleic acid metabolism is a collective term that refers to the variety of chemical reactions by which nucleic acids (DNA and/or RNA) are either synthesized or degraded. Nucleic acids are polymers (so-called "biopolymers") made up of a variety of monomers called nucleotides .

  6. Artificial gene synthesis - Wikipedia

    en.wikipedia.org/wiki/Artificial_gene_synthesis

    It comprises two main steps, the first of which is solid-phase DNA synthesis, sometimes known as DNA printing. [1] This produces oligonucleotide fragments that are generally under 200 base pairs. The second step then involves connecting these oligonucleotide fragments using various DNA assembly methods.

  7. De novo synthesis - Wikipedia

    en.wikipedia.org/wiki/De_novo_synthesis

    Cholesterol also serves as a precursor for the biosynthesis of steroid hormones, bile acid [2] and vitamin D. In mammals cholesterol is either absorbed from dietary sources or is synthesized de novo. Up to 70-80% of de novo cholesterol synthesis occurs in the liver, and about 10% of de novo cholesterol synthesis occurs in the small intestine. [3]

  8. Synthesis - Wikipedia

    en.wikipedia.org/wiki/Synthesis

    Protein biosynthesis, the multi-step biochemical synthesis of proteins (long peptides) DNA synthesis, several biochemical processes for making DNA DNA replication, DNA biosynthesis in vivo; Synthesis (cell cycle) RNA synthesis, the synthesis of RNA from nucleic acids, using another nucleic acid chain as a template

  9. DNA replication - Wikipedia

    en.wikipedia.org/wiki/DNA_replication

    Multiple DNA polymerases take on different roles in the DNA replication process. In E. coli, DNA Pol III is the polymerase enzyme primarily responsible for DNA replication. It assembles into a replication complex at the replication fork that exhibits extremely high processivity, remaining intact for the entire replication cycle.