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Schizophrenia is thought to have a heritable component in some people, but many people who appear to carry schizophrenia-associated genes may not develop the disease. [13] Research has shown that schizophrenia is a polygenic disorder and that genetic vulnerability to schizophrenia is highly multifactorial , caused by the interactions of several ...
The causes of schizophrenia that underlie the development of schizophrenia, a psychiatric disorder, are complex and not clearly understood.A number of hypotheses including the dopamine hypothesis, and the glutamate hypothesis have been put forward in an attempt to explain the link between altered brain function and the symptoms and development of schizophrenia.
An inadequate diet is often found in schizophrenia, and associated vitamin deficiencies including those of folate, and vitamin D are linked to the risk factors for the development of schizophrenia and for early death including heart disease. [226] [227] Those with schizophrenia possibly have the worst diet of all the mental disorders.
Other diseases and infections in mothers whom are pregnant have been linked to increased risk of schizophrenia. These include, mothers who have the herpes simplex virus, meningitis, and even celiac disease. In a Danish study, children whose mothers have celiac disease were two times more likely to develop schizophrenia later in life. [23]
Schizophrenia is a debilitating and often misunderstood disorder that affects up to 1% of the world's population. [1] Although schizophrenia is a heavily studied disorder, it has remained largely impervious to scientific understanding; epigenetics offers a new avenue for research, understanding, and treatment.
Risk factors for mental illness include psychological trauma, adverse childhood experiences, genetic predisposition, and personality traits. [7] [8] Correlations between mental disorders and substance use are also found to have a two way relationship, in that substance use can lead to the development of mental disorders and having mental disorders can lead to substance use/abuse.
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