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On July 18, 2006, pharmaceutical company Novartis announced it would be building a manufacturing facility in Holly Springs and employing about 350 to produce flu vaccines using new technologies. The manufacturing facility was built on 167 acres (0.68 km 2 ) in Holly Springs Business Park off N.C. 55 Bypass.
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In April 2007, Novartis received a positive opinion supporting European Union approval of Optaflu. It is the first influenza vaccine made in a mammalian cell line, rather than chicken eggs. [15] The plan was to manufacture the vaccine in Holly Springs, North Carolina. The United States government provided $500 million in construction costs and ...
In January 2009, the United States Department of Health and Human Services awarded Novartis a $486 million contract for construction of the first US plant to produce cell-based influenza vaccine, to be located in Holly Springs, North Carolina.
Holly Springs is an unincorporated community located in the Mount Airy Township of Surry County, North Carolina, United States. The community is generally centered on the intersection of Holly Springs Road and Reeves Mill Road, southeast of Bannertown. The Mount Airy/Surry County Airport is located in Holly Springs. Other prominent landmarks ...
In 1949 or 1950, NC 273 was extended north again, along NC 16, then west on an upgraded road to NC 27, near Goodsonville. In 1967, NC 273 was moved back to its northern terminus at NC 16; the highway between NC 16 and NC 27 became part of NC 73. Between 1980 and 1982, NC 273 was extended south to its current southern terminus at NC 279. In 1988 ...
Passing between Apex to the north and Holly Springs to the south, the route has an interchange with NC 540 (Triangle Expressway) and merges with US 64 as it crosses into Cary. At the Raleigh–Cary line, near the Crossroads Plaza shopping center, it has an interchange with I-40 and begins an 11-mile (18 km) concurrency with I-440 along the ...
North Carolina Highway 43 Business (NC 43 Bus) was established in 2001, when NC 43 was rerouted to bypass north of downtown Rocky Mount. The business loop travels along Cokey Road, Fairview Road, Grand Avenue, Grace Street and Falls Road.
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