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  2. Hypersegmented neutrophil - Wikipedia

    en.wikipedia.org/wiki/Hypersegmented_neutrophil

    Neutrophil hypersegmentation can be defined as the presence of neutrophils whose nuclei have six or more lobes or the presence of more than 3% of neutrophils with at least five nuclear lobes. [1] This is a clinical laboratory finding. It is visualized by drawing blood from a patient and viewing the blood smeared on a slide under a microscope ...

  3. Myelodysplastic syndrome - Wikipedia

    en.wikipedia.org/wiki/Myelodysplastic_syndrome

    The prognosis depends on the type of cells affected, the number of blasts in the bone marrow or blood, and the changes present in the chromosomes of the affected cells. [3] The average survival time following diagnosis is 2.5 years. [4] MDS was first recognized in the early 1900s; [5] it came to be called myelodysplastic syndrome in 1976. [5]

  4. Pelger–Huët anomaly - Wikipedia

    en.wikipedia.org/wiki/Pelger–Huët_anomaly

    Is a benign dominantly inherited defect of terminal neutrophil differentiation as a result of mutations in the lamin B receptor gene. The characteristic leukocyte appearance was first reported in 1928 by Karel Pelger (1885-1931), a Dutch Hematologist, who described leukocytes with dumbbell-shaped bilobed nuclei, a reduced number of nuclear segments, and coarse clumping of the nuclear chromatin.

  5. Acute myeloid leukemia - Wikipedia

    en.wikipedia.org/wiki/Acute_myeloid_leukemia

    Acute myeloid leukemia (AML) is a cancer of the myeloid line of blood cells, characterized by the rapid growth of abnormal cells that build up in the bone marrow and blood and interfere with normal blood cell production. [1] Symptoms may include feeling tired, shortness of breath, easy bruising and bleeding, and increased risk of infection. [1]

  6. File:Hypersegmented neutrophil - by Gabriel Caponetti,MD.jpg

    en.wikipedia.org/wiki/File:Hypersegmented...

    Hypersegmented_neutrophil_-_by_Gabriel_Caponetti,MD.jpg ‎ (435 × 380 pixels, file size: 76 KB, MIME type: image/jpeg) This is a file from the Wikimedia Commons . Information from its description page there is shown below.

  7. Chronic neutrophilic leukemia - Wikipedia

    en.wikipedia.org/wiki/Chronic_neutrophilic_leukemia

    Myelocytes and neutrophils are increased, and blasts and promyelocytes are not increased. Due to the myeloproliferative nature of the disease, an increase in megakaryocytes and erythroid precursors may be observed, but dyspoiesis in not seen in any cell lineage. Also, reticulin fibrosis is rare.

  8. White blood cell differential - Wikipedia

    en.wikipedia.org/wiki/White_blood_cell_differential

    A white blood cell differential is a medical laboratory test that provides information about the types and amounts of white blood cells in a person's blood. The test, which is usually ordered as part of a complete blood count (CBC), measures the amounts of the five normal white blood cell types – neutrophils, lymphocytes, monocytes, eosinophils and basophils – as well as abnormal cell ...

  9. Macrocytic anemia - Wikipedia

    en.wikipedia.org/wiki/Macrocytic_anemia

    Hypersegmented neutrophils may be seen in the absence of macroovalocytes as hypersegmentation of neutrophils is an early sign of megaloblastic anemia and may precede the appearance of macroovalocytes; they may also be seen in other anemias (e.g., iron deficiency anemia) and thus are suggestive of megaloblastic anemia but not specific for it. [1]