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  2. Empagliflozin - Wikipedia

    en.wikipedia.org/wiki/Empagliflozin

    The main efficacy measurement was the time to death from cardiovascular causes or need to be hospitalized for heart failure. [33] Of the individuals who received empagliflozin for an average of about two years, 14% died from cardiovascular causes or were hospitalized for heart failure, compared to 17% of the participants who received the ...

  3. Eli Lilly, Boehringer Share Jardiance Data In Heart ... - AOL

    www.aol.com/news/eli-lilly-boehringer-share...

    In the trial, Jardiance cut the combined risk of cardiovascular death or hospitalization from heart failure in HFpEF patients with or without diabetes. At the 26-month mark, 13.8% of Jardiance ...

  4. Lilly's (LLY) Jardiance Heart Failure Study Meets Main Goal - AOL

    www.aol.com/news/lillys-lly-jardiance-heart...

    Lilly's (LLY) Jardiance significantly reduces the risk of the composite of cardiovascular death or hospitalization for heart failure in patients with heart failure with preserved ejection fraction.

  5. Empagliflozin/linagliptin - Wikipedia

    en.wikipedia.org/wiki/Empagliflozin/linagliptin

    The most common side effects include urinary infections, nasopharyngitis, and upper respiratory tract infections . [5] [6] The most serious side effects include ketoacidosis (high blood levels of acids called ‘ketoacids’), pancreatitis (inflammation of the pancreas), hypersensitivity (allergic reactions) and hypoglycaemia (low blood sugar levels).

  6. Empagliflozin/linagliptin/metformin - Wikipedia

    en.wikipedia.org/wiki/Empagliflozin/linagliptin/...

    To reduce the risk of developing ketoacidosis (a serious condition where the body produces high levels of blood acids called ketones) after surgery, the FDA has approved changes to the prescribing information for SGLT2 inhibitor diabetes medications, recommending they be temporarily stopped before scheduled surgery.

  7. Lilly, Boehringer say Jardiance slows kidney disease ... - AOL

    www.aol.com/news/lilly-boehringer-jardiance...

    In a statement on Friday, the two partners said Jardiance cut the risk of kidney disease progression and cardiovascular death by 28%, citing results from a late-stage trial which included people ...

  8. Cardiac index - Wikipedia

    en.wikipedia.org/wiki/Cardiac_index

    Cardiac index is a critical parameter in evaluating cardiac performance and the adequacy of tissue perfusion. In healthy adults, the normal range of cardiac index is generally between 2.6 to 4.2 L/min/m². Values below this range may indicate hypoperfusion and are often seen in conditions such as heart failure, hypovolemia, and cardiogenic shock.

  9. SGLT2 inhibitor - Wikipedia

    en.wikipedia.org/wiki/SGLT2_inhibitor

    Sotagliflozin (Inpefa) is a dual SGLT1/SGLT2 inhibitor approved by the US Food and Drug Administration (FDA) in May 2023, to reduce the risk of cardiovascular death, hospitalization for heart failure, and urgent heart failure visit in adults with heart failure or type 2 diabetes, chronic kidney disease, and other cardiovascular risk factors ...

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