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Homeodomain-only protein is a protein that in humans is encoded by the HOPX gene. [5] It is an important regulator of cardiac development [ 6 ] and a marker of hippocampal neural stem cells . [ 7 ] [ 8 ]
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The HIPK2 protein is 1198 amino acids in length and has a molecular weight of 130.97 kilodaltons. [21] [22] The most abundant amino acids in the protein are serine, threonine and alanine, which make up approximately 30 percent of the proteins total amino acid count. [21] The structure of the protein in its native form is unstable. [21]
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The same Hox protein can act as a repressor at one gene and an activator at another. The ability of Hox proteins to bind DNA is conferred by a part of the protein referred to as the homeodomain. The homeodomain is a 60-amino-acid-long DNA-binding domain (encoded by its corresponding 180-base-pair DNA sequence, the homeobox
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1540 Olentangy River Rd, Columbus, OH · Directions · (614) 299-2253