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Polycystic ovary syndrome, or polycystic ovarian syndrome (PCOS), is the most common endocrine disorder in women of reproductive age. [14] The syndrome is named after cysts which form on the ovaries of some women with this condition, though this is not a universal symptom, and not the underlying cause of the disorder.
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Not all women with PCOS have difficulty becoming pregnant. For those who do, anovulation is a common cause. The mechanism of this anovulation is uncertain, but there is evidence of arrested antral follicle development, which, in turn, may be caused by abnormal interaction of insulin and luteinizing hormone (LH) on granulosa cells.
PCOS affects 8%-18% of reproductive-aged women. On average, women visit three or more health professionals before a diagnosis is established. And, the World Health Organization estimates that up ...
People with cancer may not report pain due to costs of treatment, a belief that pain is inevitable, an aversion to treatment side effects, fear of developing addiction or tolerance, fear of distracting the doctor from treating the illness, [51] or fear of masking a symptom that is important for monitoring progress of the illness.
“GLP-1 agonists can be used in place of metformin if patients didn’t previously respond at all to metformin or if they did not tolerate it because of side effects,” Kumar said.
The increased metabolic rate and appetite suppression that is also common in cachexia can compound muscle loss and make it worse. [9] Studies using a calorie-dense protein supplementation have suggested at least weight stabilization can be achieved, although improvements in lean body mass have not been observed in these studies.
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