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3357 15559 Ensembl ENSG00000135914 ENSMUSG00000026228 UniProt P41595 Q02152 RefSeq (mRNA) NM_000867 NM_001320758 NM_008311 RefSeq (protein) NP_000858 NP_001307687 NP_032337 Location (UCSC) Chr 2: 231.11 – 231.13 Mb Chr 1: 86.03 – 86.04 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse 5-Hydroxytryptamine receptor 2B (5-HT 2B) also known as serotonin receptor 2B is a protein that in ...
The 7 general serotonin receptor classes include a total of 14 known serotonin receptors. [9] The 15th receptor 5-HT 1P has been distinguished on the basis of functional and radioligand binding studies, its existence has never been definitely affirmed or refuted. [10] [11] The specific types have been characterized as follows: [12] [13] [14]
The serotonin transporter (SERT or 5-HTT) also known as the sodium-dependent serotonin transporter and solute carrier family 6 member 4 is a protein that in humans is encoded by the SLC6A4 gene. [5] SERT is a type of monoamine transporter protein that transports the neurotransmitter serotonin from the synaptic cleft back to the presynaptic ...
Serotonin (/ ˌ s ɛr ə ˈ t oʊ n ɪ n, ˌ s ɪər ə-/) [6] [7] [8] or 5-hydroxytryptamine (5-HT) is a monoamine neurotransmitter.Its biological function is complex, touching on diverse functions including mood, cognition, reward, learning, memory, and numerous physiological processes such as vomiting and vasoconstriction.
15560 Ensembl n/a ENSMUSG00000041380 UniProt P28335 P34968 RefSeq (mRNA) NM_001256761 NM_000868 NM_001256760 NM_008312 RefSeq (protein) NP_000859 NP_001243689 NP_001243690 NP_032338 Location (UCSC) n/a Chr X: 145.75 – 145.98 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse The 5-HT 2C receptor is a subtype of the 5-HT2 receptor that binds the endogenous neurotransmitter serotonin (5 ...
15550 Ensembl ENSG00000178394 ENSMUSG00000021721 UniProt P08908 Q64264 RefSeq (mRNA) NM_000524 NM_008308 RefSeq (protein) NP_000515 NP_032334 Location (UCSC) Chr 5: 63.96 – 63.96 Mb Chr 13: 105.58 – 105.58 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse The serotonin 1A receptor (or 5-HT 1A receptor) is a subtype of serotonin receptors, or 5-HT receptors, that binds serotonin ...
The genes encoding human 5-HT 3 receptors are located on chromosomes 11 (HTR3A, HTR3B) and 3 (HTR3C, HTR3D, HTR3E), so it appears that they have arisen from gene duplications. The genes HTR3A and HTR3B encode the 5-HT 3A and 5-HT 3B subunits and HTR3C, HTR3D and HTR3E encode the 5-HT 3C, 5-HT 3D and 5-HT 3E subunits.
The 5-HT 7 receptor is a member of the GPCR superfamily of cell surface receptors and is activated by the neurotransmitter serotonin (5-hydroxytryptamine, 5-HT). [5] The 5-HT 7 receptor is coupled to G s (stimulates the production of the intracellular signaling molecule cAMP) [6] [7] and is expressed in a variety of human tissues, particularly in the brain, the gastrointestinal tract, and in ...