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Follicle-stimulating hormone (FSH) is a gonadotropin, a glycoprotein polypeptide hormone. [1] FSH is synthesized and secreted by the gonadotropic cells of the anterior pituitary gland [2] and regulates the development, growth, pubertal maturation, and reproductive processes of the body.
In females, an acute rise of LH known as an LH surge, triggers ovulation [4] and development of the corpus luteum. In males, where LH had also been called interstitial cell–stimulating hormone (ICSH), [5] it stimulates Leydig cell production of testosterone. [4] It acts synergistically with follicle-stimulating hormone .
2492 14309 Ensembl ENSG00000170820 ENSMUSG00000032937 UniProt P23945 P35378 RefSeq (mRNA) NM_000145 NM_181446 NM_013523 RefSeq (protein) NP_000136 NP_852111 NP_038551 Location (UCSC) Chr 2: 48.96 – 49.15 Mb Chr 17: 89.29 – 89.51 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse The follicle-stimulating hormone receptor or FSH receptor (FSHR) is a transmembrane receptor that ...
Gonadotropic cells (also known as gonadotropes, gonadotrophs, delta cells, or delta basophils) are endocrine cells in the anterior pituitary that produce gonadotropins.More specifically, gonadotrophs produce and secrete glycoprotein polypeptide hormones, such as the follicle-stimulating hormone (FSH) and luteinizing hormone (LH), which are released due to the positive input of gonadotropin ...
Research shows that older men and women with low testosterone have lower red blood cell counts and an increased risk of developing anemia. Anemia can produce symptoms like fatigue, weakness, loss ...
Gonadotropins are glycoprotein hormones secreted by gonadotropic cells of the anterior pituitary of vertebrates. [1] [2] [3] This family includes the mammalian hormones follicle-stimulating hormone (FSH) and luteinizing hormone (LH), the placental/chorionic gonadotropins, human chorionic gonadotropin (hCG) and equine chorionic gonadotropin (eCG), [3] as well as at least two forms of fish ...
Identified in 1986, [1] [2] activin enhances FSH biosynthesis and secretion, and participates in the regulation of the menstrual cycle. Many other functions have been found to be exerted by activin, including roles in cell proliferation, differentiation, apoptosis, [3] metabolism, homeostasis, immune response, wound repair, [4] and endocrine ...
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