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In humans, the kidneys are two reddish-brown bean-shaped blood-filtering organs [1] that are a multilobar, multipapillary form of mammalian kidneys, usually without signs of external lobulation. [2] [3] They are located on the left and right in the retroperitoneal space, and in adult humans are about 12 centimetres (4 + 1 ⁄ 2 inches) in length.
Mammalian kidneys are susceptible to ischemic injury because mammals lack a renal-portal system, and as a result, vascular vasoconstriction in the glomeruli can lead to decreased blood supply to the entire kidney. The kidneys are susceptible to toxic injury, since toxins are reabsorbed in the tubules along with most of the filtered substances. [47]
The renal crest usually appears in animals larger than rabbits. [68] The kidneys of bovines are multilobar with external lobation. [72] Marine mammals, bears and otters have reniculate kidneys which are made of large amount of lobes called reniculi. [73] Each renculus can be compared to a simple unipapillary kidney as a whole. [74]
It contains the renal corpuscles and the renal tubules except for parts of the loop of Henle which descend into the renal medulla. It also contains blood vessels and cortical collecting ducts. The renal cortex is the part of the kidney where ultrafiltration occurs. [2] Erythropoietin is produced in the renal cortex. [3]
This is an accepted version of this page This is the latest accepted revision, reviewed on 13 November 2024. This article is about the human urinary system. For urinary systems of other vertebrates, see Urinary systems of birds, urinary systems of reptiles, and urinary systems of amphibians. Anatomical system consisting of the kidneys, ureters, urinary bladder, and the urethra Urinary system 1 ...
The renal pelvis is the location of several kinds of kidney cancer and is affected by infection in pyelonephritis. [citation needed] A large "staghorn" kidney stone may block all or part of the renal pelvis. The size of the renal pelvis plays a major role in the grading of hydronephrosis.
Renal corpuscle showing glomerulus and glomerular capillaries Figure 2: (a) Diagram of the juxtaglomerular apparatus: it has specialized cells working as a unit which monitor the sodiujuxtaglomerular apparatus: it has three types of specm content of the fluid in the distal convoluted tubule (not labelled - it is the tubule on the left) and adjust the glomerular filtration rate and the rate of ...
Pronephros is the most basic of the three excretory organs that develop in vertebrates, corresponding to the first stage of kidney development. It is succeeded by the mesonephros, which in fish and amphibians remains as the adult kidney. In amniotes, the mesonephros is the embryonic kidney and a more complex metanephros acts as the adult kidney ...