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An alkylating antineoplastic agent is an alkylating agent used in cancer treatment that attaches an alkyl group (C n H 2n+1) to DNA. [1] Since cancer cells, in general, proliferate faster and with less error-correcting than healthy cells, cancer cells are more sensitive to DNA damage—such as being alkylated. Alkylating agents are used to ...
Alkylate is a premium gasoline blending stock because it has exceptional antiknock properties and is clean burning. Alkylate is also a key component of avgas . By combining fluid catalytic cracking , polymerization, and alkylation, refineries can obtain a gasoline yield of 70 percent.
The product of the unit, the alkylate, is composed of a mixture of high-octane, branched-chain paraffinic hydrocarbons (mostly isoheptane and isooctane). Alkylate is a premium gasoline blending stock because it has exceptional antiknock properties and is clean burning. The octane number of the alkylate depends mainly upon the kind of alkenes ...
Dexamethasone along with either bortezomib or melphalan is commonly used as a treatment for AL amyloidosis. Recently, bortezomid in combination with cyclophosphamide and dexamethasone has also shown promise as a treatment for AL amyloidosis. Other drugs used to treat myeloma such as lenalidomide have shown promise in treating AL amyloidosis. [173]
Alkylating antineoplastic agents are a class of compounds that are used to treat cancer. In such case, the term alkyl is used loosely. For example, nitrogen mustards are well-known alkylating agents, but they are not simple hydrocarbons. In chemistry, alkyl is a group, a substituent, that is attached to other molecular fragments.
"Salicylic acid is a topical medication used to treat acne and a variety of other skin conditions, like warts and psoriasis," says double-board-certified dermatologist, Maya Thosani, MD. While it ...
A small amount of castor oil can be ingested relieve occasional constipation and is safe when used at the right dosage as directed by a doctor, Dr. Adil Bharucha, a gastroenterologist at the Mayo ...
Chloro ethyl nitroso urea (CENU), specifically carmustine (BCNU), are crosslinking agents that are widely used in chemotherapy, particularly for brain tumors. These agents differ from other crosslinkers as they alkylate O 6 of guanine to form an O 6-ethanoguanine. This intermediate compound then leads to an interstrand crosslink between a GC ...