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Mood swings in major depressive disorder (MDD): Various mood patterns, [69] and mood changes erratically. [37] Mood swings occur episodically and fluctuate in moderate high mood and severe low mood. [ 70 ] [ 71 ] Characterized by having high negative affect (bad mood) most of the time, particularly in melancholic subtype. [ 72 ]
Hypothyroidism (also called underactive thyroid, low thyroid or hypothyreosis) is a disorder of the endocrine system in which the thyroid gland does not produce enough thyroid hormones. [3] It can cause a number of symptoms, such as poor ability to tolerate cold , extreme fatigue, muscle aches , constipation , slow heart rate , depression , and ...
Thyroid disease is a medical condition that affects the function of the thyroid gland. The thyroid gland is located at the front of the neck and produces thyroid hormones [1] that travel through the blood to help regulate many other organs, meaning that it is an endocrine organ. These hormones normally act in the body to regulate energy use ...
Patients with Graves' disease can also undergo periods of hypothyroidism (inadequate production of thyroid hormone; see symptoms of hypothyroidism), due to the challenges of finding the right dosage of thyroid hormone suppression and/or supplementation. The body's need for thyroid hormone can also change over time, such as in the first months ...
It is known that even subclinical hypothyroidism can blunt a patient's response to both mood stabilizers and antidepressants. Furthermore, preliminary research into the use of thyroid augmentation in patients with refractory and rapid-cycling bipolar disorder has been positive, showing a slowing in cycle frequency and reduction in symptoms.
Endocrine disorders are often quite complex, involving a mixed picture of hyposecretion and hypersecretion because of the feedback mechanisms involved in the endocrine system. For example, most forms of hyperthyroidism are associated with an excess of thyroid hormone and a low level of thyroid stimulating hormone. [2]
Mood disorders fall into seven groups, [2] including; abnormally elevated mood, such as mania or hypomania; depressed mood, of which the best-known and most researched is major depressive disorder (MDD) (alternatively known as clinical depression, unipolar depression, or major depression); and moods which cycle between mania and depression ...
Cyclothymia (/ ˌ s aɪ k l ə ˈ θ aɪ m i ə /, siy-kluh-THIY-mee-uh), also known as cyclothymic disorder, psychothemia / psychothymia, [5] bipolar III, [6] affective personality disorder [7] and cyclothymic personality disorder, [8] is a mental and behavioural disorder [9] that involves numerous periods of symptoms of depression and periods of symptoms of elevated mood. [3]
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