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In October 2008, the FDA approved Seroquel XR for the treatment of bipolar depression and bipolar mania. In December 2008, Biovail announced that the FDA had accepted the company's ANDA to market its own version of sustained-release quetiapine. [94] Biovail's sustained-release tablets will compete with AstraZeneca's Seroquel XR.
Bipolar disorder is a long-term mood disorder characterized by major fluctuations in mood — both high and low — that can impact daily functioning and behavior. ... (Seroquel XR®)
Seroquel and Seroquel XR – atypical antipsychotic used to treat schizophrenia and bipolar disorder. Used off-label to treat insomnia; Sonata – a non-benzodiazepine hypnotic; Spravato – a rapid-acting antidepressant of the NMDA receptor antagonist class; enantiomer of ketamine
5 Bipolar Disorder. ... Focalin, Focalin XR Methamphetamine: Desoxyn ... Seroquel Risperidone: Risperdal Ziprasidone: Geodon, Zeldox Depressive Disorders
Lumateperone (Caplyta) – approved as a monotherapy for bipolar depression; Lurasidone (Latuda) – approved as a monotherapy for bipolar depression; Quetiapine (Seroquel) – approved as a monotherapy for bipolar depression; Sulpiride – approved in low doses as a monotherapy for major depressive disorder [12]
A variety of other agents have been tried in bipolar disorder, including benzodiazepines, calcium channel blockers, L-methylfolate, and thyroid hormone. [2] Modafinil (Provigil) and pramipexole (Mirapex) have been suggested for treating cognitive dysfunction associated with bipolar depression, but evidence supporting their use is quite limited.
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