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Herpes zoster (shingles): the typical dosage for treatment of herpes is 1,000 mg orally three times a day for seven consecutive days. [10] Prevention of cytomegalovirus following organ transplantation; Prevention of herpesviruses in immunocompromised people (such as those undergoing cancer chemotherapy) [11] Chickenpox in children (ages 2–18) [1]
On the first day, they'd have 100 mg in their system; their body would clear 10 mg, leaving 90 mg. On the second day, the patient would have 190 mg in total; their body would clear 19 mg, leaving 171 mg. On the third day, they'd be up to 271 mg total; their body would clear 27 mg, leaving 244 mg.
Studies in rats in which they were given the equivalent to 63 times the standard steady-state human concentrations of the drug [Note 1] on day 10 of gestation showed head and tail anomalies. [ 27 ] Aciclovir is recommended by the CDC for treatment of varicella during pregnancy, especially during the second and third trimesters.
The therapeutic index (TI; also referred to as therapeutic ratio) is a quantitative measurement of the relative safety of a drug with regard to risk of overdose.It is a comparison of the amount of a therapeutic agent that causes toxicity to the amount that causes the therapeutic effect. [1]
The median effective dose is the dose that produces a quantal effect (all or nothing) in 50% of the population that takes it (median referring to the 50% population base). [6] It is also sometimes abbreviated as the ED 50, meaning "effective dose for 50% of the population". The ED50 is commonly used as a measure of the reasonable expectancy of ...
Bicalutamide is used primarily in the treatment of early and advanced prostate cancer. [1] It is approved at a dosage of 50 mg/day as a combination therapy with a gonadotropin-releasing hormone analogue (GnRH analogue) or orchiectomy (that is, surgical or medical castration) in the treatment of stage D2 metastatic prostate cancer (mPC), [2] [3] and as a monotherapy at a dosage of 150 mg/day ...
Febuxostat is used to treat chronic gout and hyperuricemia. [12] Febuxostat is typically recommended only for people who cannot tolerate allopurinol. [13] National Institute for Health and Clinical Excellence concluded that febuxostat is more effective than standard doses of allopurinol, but not more effective than higher doses of allopurinol.
As at Oct 13, 2024, solar cycle 25 is averaging 40% more spots per day than solar cycle 24 at the same point in the cycle (Oct 13, 2013). Year 1 of SC25 (Dec 2019 to Nov 2020) averaged 101% more spots per day than year 1 of SC24. Year 2 of SC25 (Dec 2020 to Nov 2021) averaged 7% more spots per day than year 2 of SC24.