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Voxel-based morphometry is a computational approach to neuroanatomy that measures differences in local concentrations of brain tissue, through a voxel-wise comparison of multiple brain images. [ 1 ] [ 2 ] In traditional morphometry , volume of the whole brain or its subparts is measured by drawing regions of interest (ROIs) on images from brain ...
For a complete display view, only one voxel per pixel (the front one) is required to be shown (although more can be used for smoothing the image), if animation is needed, the front voxels to be shown can be cached and their location relative to the camera can be recalculated as it moves.
The scanner produces a 'map' of the area that is represented as voxels. Each voxel represents the activity of a specific volume in three-dimensional space. The exact size of a voxel varies depending on the technology. fMRI voxels typically represent a volume of 27 mm 3 in an equilateral cuboid.
A T1 weighted MR image of the brain of a patient with a meningioma after injection of an MRI contrast agent (top left), and the same image with the result of an interactive segmentation overlaid in green (3D model of the segmentation on the top right, axial and coronal views at the bottom).
The voxel intensity in QSM is linearly proportional to the underlying tissue apparent magnetic susceptibility, which is useful for chemical identification and quantification of specific biomarkers including iron, calcium, gadolinium, and super paramagnetic iron oxide (SPIO) nano-particles.
The image data is provided by radiological modalities as CT, [11] MRI, [12] PET/CT or even PET/MR. [13] The produced raw data volumes are used to find different pixel/voxel characteristics through extraction tools.
Modern 3 Tesla clinical MRI scanner.. Magnetic resonance imaging (MRI) is a medical imaging technique mostly used in radiology and nuclear medicine in order to investigate the anatomy and physiology of the body, and to detect pathologies including tumors, inflammation, neurological conditions such as stroke, disorders of muscles and joints, and abnormalities in the heart and blood vessels ...
Due to the different variations of each implementations, it is recommended that a large multi-scanner study should design a protocol minimizing the variety of readout methods used by each scanner. One study has shown that although there are voxel differences when different readout methods are used, average gray matter CBF are still comparable.