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Men tend to have noticeably lower HDL concentrations, with smaller size and lower cholesterol content, than women. Men also have a greater incidence of atherosclerotic heart disease. Studies confirm the fact that HDL has a buffering role in balancing the effects of the hypercoagulable state in type 2 diabetics and decreases the high risk of ...
A deficiency of LCAT causes accumulation of unesterified cholesterol in certain body tissues. Cholesterol effluxes from cells as free cholesterol and is transported in HDL as esterified cholesterol. LCAT is the enzyme that esterifies the free cholesterol on HDL to cholesterol ester and allows the
Hypocholesterolemia is the presence of abnormally low (hypo-) levels of cholesterol in the blood (-emia).A defect in the body's production of cholesterol can lead to adverse consequences as well.
It decreases LDL by 15–30% and raises HDL by 3–5%, with little effect on triglycerides, but can cause a slight increase. Bile acid sequestrants may cause gastrointestinal problems and may also reduce the absorption of other drugs and vitamins from the gut. Ezetimibe is a selective inhibitor of dietary cholesterol absorption.
Another blood level collected to assess dyslipidemia is HDL-C. [6] HDL cholesterol is made up of very little lipids and a high amount of protein. [1] It is beneficial in the body because it functions by going to the tissues and picking up extra cholesterol and fat. [1]
The risk of developing type 2 diabetes, stroke, and depression may be higher in people with a "sweet tooth" who prefer sugary foods, new research suggests.
After a meal, when the blood concentration of fatty acids rises, there is an increase in uptake of fatty acids in different cells of the body, mainly liver cells, adipocytes and muscle cells. This uptake is stimulated by insulin from the pancreas. As a result, the blood concentration of fatty acid stabilizes again after a meal.
Niacin, or vitamin B 3 has a mechanism of action that is poorly understood, however it has been shown to decrease LDL cholesterol and triglycerides, and increase HDL cholesterol. [55] The most common side effect is flushing secondary to skin vasodilation. [55] This effect is mediated by prostaglandins and can be decreased by taking concurrent ...
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