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This study demonstrates a rapid-onset antidepressant effect of ketamine in a small group of patients with bipolar depression. The authors acknowledged the study's limitations, including the dissociative disturbances in patients receiving ketamine that could have compromised the study blinding , and they emphasised the need for further research.
Symptoms of Bipolar Disorder. The single most telling symptom of bipolar disorder is the episodic oscillation between high and low mood states — characteristic shifts between depression, normal ...
Lumateperone (Caplyta) – approved as a monotherapy for bipolar depression; Lurasidone (Latuda) – approved as a monotherapy for bipolar depression; Quetiapine (Seroquel) – approved as a monotherapy for bipolar depression; Sulpiride – approved in low doses as a monotherapy for major depressive disorder [12]
Mood stabilizers are best known for the treatment of bipolar disorder, [1] preventing mood shifts to mania (or hypomania) and depression. Mood stabilizers are also used in schizoaffective disorder when it is the bipolar type. [2]
As an SSRI antidepressant, escitalopram is commonly prescribed to treat depression. The FDA also approves it for the treatment of generalized anxiety disorder (GAD).
Most of the weight gain caused by antidepressants is mild, with a 2017 study from Australia finding that high-dosage antidepressant users gain 0.28kg (about 0.6 lbs) per year on average.
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