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CD1 (cluster of differentiation 1) is a family of glycoproteins expressed on the surface of various human antigen-presenting cells.CD1 glycoproteins are structurally related to the class I MHC molecules, however, in contrast to MHC class 1 proteins, they present lipids, glycolipids and small molecules antigens, from both endogenous and pathogenic proteins, to T cells and activate an immune ...
Neuropilin-1 (NP-1), NRP1 or BDCA-4, has a wide range of functions. On neurons , it is a receptor for axon growth guidance class-3 semaphorins SEMA3A and plexin-1, on endothelial and some tumor cells it is a VEGF 165 receptor, and on plasmacytoid dendritic cells it has a similar role to CD303 but does not decrease interferon production upon ...
The CD nomenclature was proposed and established in the 1st International Workshop and Conference on Human Leukocyte Differentiation Antigens (HLDA), held in Paris in 1982. [4] [5] This system was intended for the classification of the many monoclonal antibodies (mAbs) generated by different laboratories around the world against epitopes on the surface molecules of leukocytes (white blood cells).
952 12494 Ensembl ENSG00000004468 ENSMUSG00000029084 UniProt P28907 P56528 RefSeq (mRNA) NM_001775 NM_007646 RefSeq (protein) NP_001766 NP_031672 Location (UCSC) Chr 4: 15.78 – 15.85 Mb Chr 5: 44.03 – 44.07 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse CD38 (cluster of differentiation 38), also known as cyclic ADP ribose hydrolase, is a glycoprotein found on the surface of many ...
[5] [6] In humans, CD19 is expressed in all B lineage cells. [ 7 ] [ 8 ] Contrary to some early doubts, human plasma cells do express CD19. [ 9 ] [ 10 ] CD19 plays two major roles in human B cells : on the one hand, it acts as an adaptor protein to recruit cytoplasmic signaling proteins to the membrane; on the other, it works within the CD19 ...
15894 Ensembl ENSG00000090339 ENSMUSG00000037405 UniProt P05362 P13597 RefSeq (mRNA) NM_000201 NM_010493 RefSeq (protein) NP_000192 NP_034623 Location (UCSC) Chr 19: 10.27 – 10.29 Mb Chr 9: 20.93 – 20.94 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse ICAM-1 (Intercellular Adhesion Molecule 1) also known as CD54 (C luster of D ifferentiation 54) is a protein that in humans is ...
Due to this functionality, adhesions and adhesion molecules have been a topic of study within the scientific community. Specifically, it has been found that adhesions are involved in tissue development, plasticity, and memory formation within the central nervous system (CNS), and may prove vital in the generation of CNS-specific therapeutics.
CD2 is a specific marker for T cells and NK cells, and can therefore be used in immunohistochemistry to identify the presence of such cells in tissue sections. The great majority of T cell lymphomas and leukaemias also express CD2, making it possible to use the presence of the antigen to distinguish these conditions from B cell neoplasms.