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The area under the effect curve (AUEC) is an integral of the effect of a drug over time, estimated as a previously-established function of concentration. It was proposed to be used instead of AUC in animal-to-human dose translation, as computer simulation shows that it could cope better with half-life and dosing schedule variations than AUC.
In probability and statistics, the 97.5th percentile point of the standard normal distribution is a number commonly used for statistical calculations. The approximate value of this number is 1.96 , meaning that 95% of the area under a normal curve lies within approximately 1.96 standard deviations of the mean .
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Taking an example, the area under the curve y = x 2 over [0, 2] can be procedurally computed using Riemann's method. The interval [0, 2] is firstly divided into n subintervals, each of which is given a width of 2 n {\displaystyle {\tfrac {2}{n}}} ; these are the widths of the Riemann rectangles (hereafter "boxes").
A 2016 Science paper reports that the trapezoid rule was in use in Babylon before 50 BCE for integrating the velocity of Jupiter along the ecliptic. [1]In 1994, a paper titled "A Mathematical Model for the Determination of Total Area Under Glucose Tolerance and Other Metabolic Curves" was published, only to be met with widespread criticism for rediscovering the Trapezoidal Rule and coining it ...
In a graphical representation of the continuous uniform distribution function [()], the area under the curve within the specified bounds, displaying the probability, is a rectangle. For the specific example above, the base would be 16 , {\displaystyle 16,} and the height would be 1 23 . {\displaystyle {\tfrac {1}{23}}.} [ 5 ]
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