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The concerns began with the hypothesis that BPA is an endocrine disruptor, i.e. it mimics endocrine hormones and thus has the unintended and possibly far-reaching effects on people in physical contact with the chemical. Since 2008, several governments have investigated its safety, which prompted some retailers to withdraw polycarbonate products.
Endocrine disruptors are chemicals that interfere with our endocrine systems, which control the body’s hormones—such as insulin, testosterone, and estrogen—and numerous bodily functions ...
Endocrine-disrupting chemicals are not produced by the human body but influence the way your hormones function, Bloom said. Hormones are essential to many biological processes in the body, such as ...
Bisphenols A (BPA), F (BPF) and S (BPS) have been shown to be endocrine disruptors, potentially relating to adverse health effects. [3] [6] Due to its high production volumes, BPA has been characterised as a "pseudo-persistent" chemical, [7] leading to its spreading and potential accumulation in a variety of environmental matrices, even though it has a fairly short half-life.
Xenoestrogens are a type of xenohormone that imitates estrogen.They can be either synthetic or natural chemical compounds.Synthetic xenoestrogens include some widely used industrial compounds, such as PCBs, BPA, and phthalates, which have estrogenic effects on a living organism even though they differ chemically from the estrogenic substances produced internally by the endocrine system of any ...
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When present in excessive amounts in the human body, xenohormones can cause a host of health issues due to their disruption of the endocrine system. The name given to these exogenous (coming from an external source) hormones is endocrine disruptors, due to their tendency to mimic the behaviors of naturally produced bodily hormones. [15]
A comparison of the structures of the natural estrogen hormone estradiol (left) and one of the nonyl-phenols (right), a xenoestrogen endocrine disruptor. Endocrine disruptors, sometimes also referred to as hormonally active agents, [1] endocrine disrupting chemicals, [2] or endocrine disrupting compounds [3] are chemicals that can interfere with endocrine (or hormonal) systems. [4]