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A container with cream. Topical cream formulation is an emulsion semisolid dosage form that is used for skin external application. Most of the topical cream formulations contain more than 20 per cent of water and volatiles and/or less than 50 per cent of hydrocarbons, waxes, or polyethylene glycols as the vehicle for external skin application. [1]
Cream. A cream is a preparation usually for application to the skin.Creams for application to mucous membranes such as those of the rectum or vagina are also used. Creams may be considered pharmaceutical products, since even cosmetic creams are manufactured using techniques developed by pharmacy and unmedicated creams are highly used in a variety of skin conditions (dermatoses).
The invention of cold cream is credited to Galen, a physician in second century Greece. [2] The original formulation involved rose water, beeswax, and either almond or olive oil. The beeswax is essential to a successful cream, as it is the emulsifying ingredient, but it is extremely inefficient compared to modern emulsifiers.
A medical professional administering nose drops Instillation of eye drops. A topical medication is a medication that is applied to a particular place on or in the body. Most often topical medication means application to body surfaces such as the skin or mucous membranes to treat ailments via a large range of classes including creams, foams, gels, lotions, and ointments. [1]
Mexican crema (or cream espesa) is similar to crème fraîche. Smetana is a heavy cream-derived (15–40% milk fat) Central and Eastern European sweet or sour cream.
[5] [3] The gelators may precipitate and salt out, and some drugs may degrade in gel formulation due to the other ingredients present in the formulation. [ 5 ] Some additives and gelators added into the formulation may cause irritation problems, [ 5 ] [ 8 ] such as skin irritation, dermatitis or allergic conditions . [ 2 ]
Aqueous Cream BP, also known as sorbolene, is a light, hydrocarbon-based emulsion, which is officially registered in the British Pharmacopoeia and categorised by the British National Formulary as a non-proprietary emollient preparation. [1]
Pharmaceutical formulation, in pharmaceutics, is the process in which different chemical substances, including the active drug, are combined to produce a final medicinal product. The word formulation is often used in a way that includes dosage form .