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Loop diuretics usually have a ceiling effect whereby doses greater than a certain maximum amount will not increase the clinical effect of the drug. Also, there is a threshold minimum concentration of loop diuretics that needs to be achieved at the thick ascending limb to enable the onset of abrupt diuresis. [10]
The threshold for light sensitivity is much higher in infants compared to adults. From birth, the pupils of an infant remain constricted to limit the amount of entering light. In regards to pupil dimensions, newborns' pupils grow from approximately 2.2 mm to an adult length of 3.3 mm. [ 2 ] A one-month-old infant can detect a light threshold ...
The Apgar score is a quick way for health professionals to evaluate the health of all newborns at 1 and 5 minutes after birth and in response to resuscitation. [1] It was originally developed in 1952 by an anesthesiologist at Columbia University, Virginia Apgar, to address the need for a standardized way to evaluate infants shortly after birth.
According to the BCM model, when a pre-synaptic neuron fires, the post-synaptic neurons will tend to undergo LTP if it is in a high-activity state (e.g., is firing at high frequency, and/or has high internal calcium concentrations), or LTD if it is in a lower-activity state (e.g., firing in low frequency, low internal calcium concentrations). [1]
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Low-threshold spikes (LTS) refer to membrane depolarizations by the T-type calcium channel. LTS occur at low, negative, membrane depolarizations. LTS occur at low, negative, membrane depolarizations. They often follow a membrane hyperpolarization , which can be the result of decreased excitability or increased inhibition.
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