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The metaplastic epithelium is at the junction (center of image) and has an intensely eosinophilic (bright pink) cytoplasm. H&E stain . Metaplasia (from Greek 'change in form') is the transformation of a cell type to another cell type. [ 1 ]
There is large amounts of research focused on finding the specific enzymes and intracellular pathways involved in the NMDAR-mediated modulation of membrane AMPA receptors. Recent biochemical research has shown that a deficiency in the protein tenascin-R (TNR) leads to a metaplastic increase in the threshold for LTP induction. TNR is an ...
Common sites for squamous metaplasia include the bladder and cervix. Smokers often exhibit squamous metaplasia in the linings of their airways. These changes don't signify a specific disease, but rather usually represent the body's response to stress or irritation.
Metaplastic carcinoma, otherwise known as metaplastic breast cancer (MBC), is a heterogeneous group of cancers that exhibit varied patterns of metaplasia and ...
Barrett's esophagus is a condition in which there is an abnormal (metaplastic) change in the mucosal cells lining the lower portion of the esophagus, from stratified squamous epithelium to simple columnar epithelium with interspersed goblet cells that are normally present only in the small intestine and large intestine.
Intestinal metaplasia is the transformation of epithelium (usually of the stomach or the esophagus) into a type of epithelium resembling that found in the intestine.In the esophagus, this is called Barrett's esophagus.
Autoimmune metaplastic atrophic gastritis (AMAG) is an inherited form of atrophic gastritis characterized by an immune response directed toward parietal cells and intrinsic factor. [ 6 ] Achlorhydria induces G cell (gastrin-producing) hyperplasia, which leads to hypergastrinemia.
A Hürthle cell is a transformed thyroid follicular cell with "enlarged mitochondria and enlarged round nuclei with prominent nucleoli", resulting in eosinophilia in the cytoplasm.