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Hydroxocobalamin, also known as vitamin B 12a and hydroxycobalamin, is a vitamin found in food and used as a dietary supplement. [1] As a supplement it is used to treat vitamin B12 deficiency including pernicious anemia.
Pernicious anemia is the most common cause of clinically evident vitamin B 12 deficiency worldwide. [14] Pernicious anemia due to autoimmune problems occurs in about one per 1000 people in the US. Among those over the age of 60, about 2% have the condition. [8] It more commonly affects people of northern European descent. [2]
Vitamin B 12 was discovered as a result of pernicious anemia, an autoimmune disorder in which the blood has a lower than normal number of red blood cells, due to a deficiency of vitamin B 12. [5] [16] The ability to absorb the vitamin declines with age, especially in people over 60. [17]
That includes folks with an autoimmune disorder called pernicious anemia, who are unable to absorb B12, and people who take a lot of over-the-counter stomach-acid reducers, like famotidine ...
Despite the low amounts absorbed, oral vitamin B 12 therapy is effective at reducing symptoms of pernicious anemia. [22] Vitamin B 12 can also be given sublingually, but there is no evidence that this route of administration is superior to the oral route, [23] and only Canada and Sweden routinely prescribe this route of administration. [20]
These editor-approved b12 supplements are third-party tested and certified and can help improve vitamin B12 levels in the body for optimal nutrition. Kick Vitamin B12 Deficiency to the Curb With ...
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