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Hepatocellular carcinoma (HCC [1]) is the most common type of primary liver cancer in adults and is currently the most common cause of death in people with cirrhosis. [2] HCC is the third leading cause of cancer-related deaths worldwide.
For example, it is recommended that people with chronic liver disease who are at risk for hepatocellular carcinoma be screened every 6 months using ultrasound imaging. [8] Because liver cancer is an umbrella term for many types of cancer, the signs and symptoms depend on what type of cancer is present. Symptoms can be vague and broad.
Molecular categorization via biopsy and pathological analysis aids in both diagnosis and understanding prognosis, particularly because hepatocellular adenomas have the potential to become malignant. [2] [7] It is important to note, percutaneous biopsy should be avoided, because this method can lead to bleeding or rupture of the adenoma. [7]
Hepatocellular carcinoma is the most common primary liver cancer, and the most common cause of death in people with cirrhosis. [151] Screening using an ultrasound with or without cancer markers such as alpha-fetoprotein can detect this cancer and is often carried out for early signs which has been shown to improve outcomes. [2] [152]
Immunohistochemistry is useful in the diagnosis and may be used to help differentiate a cholangiocarcinoma from hepatocellular carcinoma and metastasis of other gastrointestinal tumors. [65] Cytological scrapings are often nondiagnostic, [ 66 ] as these tumors typically have a desmoplastic stroma and, therefore, do not release diagnostic tumor ...
Fibrolamellar carcinoma (FLC) is a rare form of carcinoma that typically affects young adults and is characterized, under the microscope, by laminated fibrous layers interspersed between the tumor cells. [1] It has been estimated that 200 new cases are diagnosed worldwide each year. [2]
The rationale for the use of bland embolization for hepatocellular carcinoma (HCC) and/or other hyper-vascular tumors is based on the fact that a normal liver receives a dual blood supply from the hepatic artery (25%) and the portal vein (75%). As the tumor grows, it becomes increasingly dependent on the hepatic artery for blood supply.
Toggle Signs and symptoms subsection. 1.1 Chronic liver disease. 1.2 Decompensation. 1.3 Signs associated with the cause. 1.4 Complications. ... Hepatocellular ...