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  2. Mechanism of action of aspirin - Wikipedia

    en.wikipedia.org/wiki/Mechanism_of_action_of_aspirin

    When high doses of aspirin are given, aspirin may actually cause hyperthermia due to the heat released from the electron transport chain, as opposed to the antipyretic action of aspirin seen with lower doses. Additionally, aspirin induces the formation of NO-radicals in the body, which have been shown in mice to have an independent mechanism of ...

  3. Aspirin - Wikipedia

    en.wikipedia.org/wiki/Aspirin

    Nine years later however, the USPSTF issued a grade B recommendation for the use of low-dose aspirin (75 to 100 mg/day) "for the primary prevention of CVD [cardiovascular disease] and CRC in adults 50 to 59 years of age who have a 10% or greater 10-year CVD risk, are not at increased risk for bleeding, have a life expectancy of at least 10 ...

  4. Daily low-dose aspirin has its benefits — and risks. Here's ...

    www.aol.com/lifestyle/aspirin-every-day-why-not...

    For years, doctors recommended that older adults at a higher risk for heart attack or stroke take a low-dose aspirin once a day to lower their risk. Aspirin helps prevent blood clots from forming ...

  5. Antihypertensive - Wikipedia

    en.wikipedia.org/wiki/Antihypertensive

    Antihypertensive therapy seeks to prevent the complications of high blood pressure, such as stroke, heart failure, kidney failure and myocardial infarction. Evidence suggests that reduction of the blood pressure by 5 mmHg can decrease the risk of stroke by 34% and of ischaemic heart disease by 21%, and can reduce the likelihood of dementia ...

  6. Management of hypertension - Wikipedia

    en.wikipedia.org/wiki/Management_of_hypertension

    For most people, recommendations are to reduce blood pressure to less than or equal to somewhere between 140/90 mmHg and 160/100 mmHg. [2] In general, for people with elevated blood pressure, attempting to achieve lower levels of blood pressure than the recommended 140/90 mmHg will create more harm than benefits, [3] in particular for older people. [4]

  7. Blood pressure - Wikipedia

    en.wikipedia.org/wiki/Blood_pressure

    There is an ongoing medical debate over what is the optimal level of blood pressure to target when using drugs to lower blood pressure with hypertension, particularly in older people. [ 13 ] Blood pressure fluctuates from minute to minute and normally shows a circadian rhythm over a 24-hour period, [ 14 ] with highest readings in the early ...

  8. These vascular risks are strongly associated with severe ...

    www.aol.com/controlling-three-things-prevent...

    High blood pressure, also known as hypertension, can result from an unhealthy lifestyle or certain health conditions, such as diabetes or obesity. The condition can also occur during pregnancy ...

  9. Comparison of international blood pressure guidelines

    en.wikipedia.org/wiki/Comparison_of...

    BP >140/90 and low-risk for CVD: Lifestyle changes BP >140/90 and CVD risk factors or failed lifestyle changes: monotherapy with thiazide-type diuretic, ACEI/ARB, and/or CCB BP >160/100: Two from different classes: thiazide-type diuretic, ACEI/ARB, and/or CCB VA/DoD 2020 [9] General Age ≥60 Age ≥60 with diabetes <130/90 <150/90 <140/90