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Mitigation may be by supplementary oxygen, pressurisation of the habitat or environmental protection suit, or a combination of both. In all cases the critical effect is the raising of oxygen partial pressure in the breathing gas. [1] Room air at altitude can be enriched with oxygen without introducing an unacceptable fire hazard.
Altitude acclimatization is the process of adjusting to decreasing oxygen levels at higher elevations, in order to avoid altitude sickness. [17] Once above approximately 3,000 metres (10,000 ft) – a pressure of 70 kilopascals (0.69 atm) – most climbers and high-altitude trekkers take the "climb-high, sleep-low" approach.
The human body has optimal endurance below 150 m (490 ft) elevation. [6] The concentration of oxygen (O 2) in air is 20.9% so the partial pressure of O 2 (PO 2) at sea level is about 21.2 kPa (6.3 inHg; 3.07 psi). In healthy individuals, this saturates hemoglobin, the oxygen-binding red pigment in red blood cells. [7]
At 11,900 m (39,000 ft), breathing pure oxygen through an unsealed face mask, one is breathing the same partial pressure of oxygen as one would experience with regular air at around 3,600 m (11,800 ft) above sea level [citation needed]. At higher altitudes, oxygen must be delivered through a sealed mask with increased pressure, to maintain a ...
An oxygen partial pressure equivalent to sea level can be maintained at an altitude of 10,000 metres (34,000 ft) with 100% oxygen. Above 12,000 metres (40,000 ft), positive pressure breathing with 100% oxygen is essential, as without positive pressure even very short exposures to altitudes above 13,000 metres (43,000 ft) lead to loss of ...
[3] [9] [15] Giving oxygen at flow rates high enough to maintain an SpO 2 at or above 90% is a fair substitute for descent. [3] [9] [15] In the hospital setting, oxygen is generally given by nasal cannula or face mask for several hours until the person is able to maintain oxygen saturations above 90% while breathing the surrounding air. [3]
Normally, the pulmonary artery supplies oxygen-filled blood from the lungs to the heart. But with this condition, the arteries are blocked, narrowed, or even destroyed, preventing healthy blood flow.
By contrast, the women of long-resident, high-altitude populations are known to give birth to heavier-weight infants than women of the lowland. This is particularly true among Tibetan babies, whose average birth weight is 294–650g (~470) g heavier than the surrounding Chinese population, and their blood-oxygen level is considerably higher. [24]