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Biguanide (/ b aɪ ˈ ɡ w ɒ n aɪ d /) is the organic compound with the formula HN(C(NH)NH 2) 2. It is a colorless solid that dissolves in water to give a highly basic solution. It is a colorless solid that dissolves in water to give a highly basic solution.
Polyhexanide (polyhexamethylene biguanide, PHMB) is a polymer used as a disinfectant and antiseptic. In dermatological use, [ 4 ] it is spelled polihexanide ( INN ) and sold under various brand names. [ 5 ]
The lactic acidosis occurred only in patients with a buformin plasma level of greater than 0.60 μg/mL and was rare in patients with normal renal function. [ 19 ] [ 20 ] [ 21 ] In one report, the toxic oral dose was 329 ± 30 mg/day in 24 patients who developed lactic acidosis on buformin.
The researchers analyzed historical data on childhood blood-lead levels, leaded gas use and U.S. population statistics, determining that more than 170 million Americans had "clinically concerning ...
In the days after UnitedHealthcare CEO Brian Thompson was gunned down in New York City, many social media users took it upon themselves to try to solve the mystery of who killed him — and why.
Based on the statements and interviews that have been made public so far, the news of Luigi Mangione’s arrest seems to have come as a shock to those who knew him.
Polyaminopropyl biguanide (PAPB) is a polymer containing biguanide group connected with a three methylene (propyl) linker. The polymer is a propyl analogue of polyhexamethylene biguanide . The polymer display some antibacterial activity however much lower than PHMB.
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