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However, environmental factors (almost certainly diet and weight) play a large part in the development of type 2 diabetes in addition to any genetic component. Genetic risk for type 2 diabetes changes as humans first began migrating around the world, implying a strong environmental component has affected the genetic-basis of type 2 diabetes.
The development of type 2 diabetes is caused by a combination of lifestyle and genetic factors. [27] [32] While some of these factors are under personal control, such as diet and obesity, other factors are not, such as increasing age, female sex, and genetics. [10] Generous consumption of alcohol is also a risk factor. [33]
Although many variables individually contribute to an increased risk of developing a substance use disorder, no single vulnerability guarantees the development of addiction. It is the combination of many factors (e.g. genetics, environmental stressors, initiation and continued use of the drug) that culminates in the development of this disorder.
Alcohol abuse during adolescence greatly increases the risk of developing an alcohol use disorder in adulthood due to changes to neurocircuitry in the vulnerable adolescent brain. [50] Younger ages of initial consumption among males in recent studies has shown to be associated with increased rates of alcohol abuse within the general population.
You don’t have to partake in binge drinking or have alcohol use disorder to increase your risk of alcohol-associated cancer. (Gregory Lee—Getty Images) This story was originally featured on ...
Substance dependence, also known as drug dependence, is a biopsychological situation whereby an individual's functionality is dependent on the necessitated re-consumption of a psychoactive substance because of an adaptive state that has developed within the individual from psychoactive substance consumption that results in the experience of withdrawal and that necessitates the re-consumption ...
FAS disrupts normal development of the fetus, which may cause certain developmental stages to be delayed, skipped, or immaturely developed. [14] Since alcohol elimination is slow in a fetus than in an adult and the fact that they do not have a developed liver to metabolize the alcohol, alcohol levels tend to remain high and stay in the fetus ...
Metabolic syndrome is associated with the risk of developing cardiovascular disease and type 2 diabetes. [1] In the U.S., about 25% of the adult population has metabolic syndrome, a proportion increasing with age, particularly among racial and ethnic minorities. [2] [3]