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  2. Direct factor Xa inhibitors - Wikipedia

    en.wikipedia.org/wiki/Direct_factor_Xa_inhibitors

    Side effects may include bleeding, most commonly from the nose, gastrointestinal tract (GI) or genitourinary system. [2] Compared to the risk of bleeding with warfarin use, direct factor Xa inhibitors have a higher risk of GI bleeding, but lower risk of bleeding in the brain. [2]

  3. Rivaroxaban - Wikipedia

    en.wikipedia.org/wiki/Rivaroxaban

    Rivaroxaban, sold under the brand name Xarelto among others, is an anticoagulant medication (blood thinner) used to treat and prevent blood clots. [8] Specifically it is used to treat deep vein thrombosis and pulmonary emboli and prevent blood clots in atrial fibrillation and following hip or knee surgery. [ 8 ]

  4. Drug interaction - Wikipedia

    en.wikipedia.org/wiki/Drug_interaction

    As of 2008, among adults in the United States of America older than 56, 4% were taking medication and/ or supplements that put them at risk of a major drug interaction. [30] Potential drug-drug interactions have increased over time [ 31 ] and are more common in the less-educated elderly even after controlling for age, sex, place of residence ...

  5. How Herbal Supplements Can Interfere with Medications ... - AOL

    www.aol.com/herbal-supplements-interfere...

    Additionally, Phillipps tells us, “Turmeric has blood-thinning properties that may amplify the effects of anticoagulants like warfarin, rivaroxaban and apixaban, increasing the risk of bleeding ...

  6. Polypharmacy - Wikipedia

    en.wikipedia.org/wiki/Polypharmacy

    [46] 15% of older adults are potentially at risk for a major drug-drug interaction. [47] Older adults are at a higher risk for a drug-drug interaction due to the increased number of medications prescribed and metabolic changes that occur with aging. [48] When a new drug is prescribed, the risk of interactions increases exponentially.

  7. Russian woman charged with sneaking aboard Delta Air Lines ...

    www.aol.com/russian-woman-charged-sneaking...

    A woman accused of sneaking onto a Delta Air Lines flight from New York to Paris was arraigned last week and charged with knowingly stowing away aboard an aircraft without consent.. Svetlana Dali ...

  8. How Did Tamales Become a Christmas Tradition? - AOL

    www.aol.com/did-tamales-become-christmas...

    It’s tamale time. This Mexican comfort food has a long history and is an essential part of every major holiday, particularly Christmas. It’s also the perfect portable snack for holiday travelers.

  9. Discovery and development of direct Xa inhibitors - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    Rivaroxaban. During the SAR development of rivaroxaban, researchers realized that adding a 5-chlorothiophene-2-carboxamide group to the oxazolidonine core could increase the potency by 200 fold, which had previously been too weak for medical use. In addition to this discovery, a clear preference for the (S)-configuration was confirmed.