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  2. What is ketamine, the drug responsible for ‘Friends’ star ...

    www.aol.com/finance/ketamine-potential-dangers...

    It can also be smoked with tobacco. The trip, called the "K hole," usually lasts two hours or less. During this time, users may become nauseated, vomit, and/or have thinking and memory problems.

  3. Recreational drug use - Wikipedia

    en.wikipedia.org/wiki/Recreational_drug_use

    The Smokers, a 1636 portrait by Adriaen Brouwer Drinking Man and an Old Smoking Man, an 18th-century portrait by anonymous author L'Absinthe, an 1876 portrait by Edgar Degas Recreational drug use is the use of one or more psychoactive drugs to induce an altered state of consciousness , either for pleasure or for some other casual purpose or ...

  4. List of polysubstance combinations - Wikipedia

    en.wikipedia.org/wiki/List_of_polysubstance...

    Similar to Jedi flipping, but with a heavy dissociative effect induced by ketamine. The substances are taken in the order of LSD, Mushrooms, MDMA, then ketamine. Each substance should be taken at the peak of the previous substance to maximize the synergistic effects. Ketamine can be re-dosed as needed to extend the trip.

  5. Ketamine - Wikipedia

    en.wikipedia.org/wiki/Ketamine

    Ketamine can be absorbed by many different routes due to both its water and lipid solubility. Intravenous ketamine bioavailability is 100% by definition, intramuscular injection bioavailability is slightly lower at 93%, [7] and epidural bioavailability is 77%. [9] Subcutaneous bioavailability has never been measured but is presumed to be high ...

  6. Here’s What You Need to Know About Ketamine, the Drug ... - AOL

    www.aol.com/lifestyle/know-ketamine-drug-linked...

    Ketamine can be concerning if it’s mixed with other drugs, Alan says. “When ketamine is mixed with things like alcohol and opioids, it can make the effects of these drugs greater,” she says.

  7. With arrests in Matthew Perry death, is L.A.'s ketamine ... - AOL

    www.aol.com/news/arrests-matthew-perry-death-l...

    Ketamine, a legal medication commonly used as an anesthetic, has gained popularity in recent years as both a clinical treatment for depression and a recreational drug. But Perry's death and the ...

  8. Free base - Wikipedia

    en.wikipedia.org/wiki/Free_base

    Alternatively, the free base can be obtained using an organic chemistry technique called trituration. Trituration of the free base from cocaine hydrochloride (or "cooking") is done by dissolving the cocaine hydrochloride in water over constant heat, while simultaneously adding a base (such as baking soda) to form the free base cocaine.

  9. Has ketamine’s time of reckoning arrived? 5 things to know ...

    www.aol.com/news/helpful-harmful-ketamine-5...

    Ketamine can be a lifeline for certain people who have not responded to common treatments for depression, such as medications and different forms of psychotherapy. “(It’s) probably the biggest ...