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  2. Mitochondrial replacement therapy - Wikipedia

    en.wikipedia.org/wiki/Mitochondrial_replacement...

    Mitochondrial replacement therapy (MRT), sometimes called mitochondrial donation, is the replacement of mitochondria in one or more cells to prevent or ameliorate disease. MRT originated as a special form of in vitro fertilisation in which some or all of the future baby's mitochondrial DNA (mtDNA) comes from a third party.

  3. 'Three-parent baby' test success could mean human trials in ...

    www.aol.com/news/2016-06-08-three-parent-baby...

    But after years of restricted research and testing on donor eggs, scientists at Newcastle University have successfully tested their mitochondrial replacement therapy (MRT) method in healthy human ...

  4. Assisted reproductive technology - Wikipedia

    en.wikipedia.org/wiki/Assisted_reproductive...

    Other assisted reproduction techniques include: Mitochondrial replacement therapy (MRT, sometimes called mitochondrial donation) is the replacement of mitochondria in one or more cells to prevent or ameliorate disease. MRT originated as a special form of IVF in which some or all of the future baby's mitochondrial DNA comes from

  5. John J. Zhang - Wikipedia

    en.wikipedia.org/wiki/John_J._Zhang

    He made headlines in September 2016 for successfully producing the world's first three-parent baby using the spindle transfer technique of mitochondrial replacement. [ 2 ] [ 3 ] Having obtained an M.D. from Zhejiang University School of Medicine , an M.Sc. from University of Birmingham , and a Ph.D. from University of Cambridge , he became the ...

  6. Shoukhrat Mitalipov - Wikipedia

    en.wikipedia.org/wiki/Shoukhrat_Mitalipov

    A therapy for mitochondrial diseases that Mitalipov discovered, the "spindle transfer" technique, involves removing the nucleus from a human egg and placing it into another. [2] [3] If the egg is fertilized, in genetic terms it would have three parents. [3] Mitalipov has successfully bred "three-parent" rhesus macaques. [3]

  7. Mitochondrial DNA - Wikipedia

    en.wikipedia.org/wiki/Mitochondrial_DNA

    An IVF technique known as mitochondrial donation or mitochondrial replacement therapy (MRT) results in offspring containing mtDNA from a donor female, and nuclear DNA from the mother and father. In the spindle transfer procedure, the nucleus of an egg is inserted into the cytoplasm of an egg from a donor female which has had its nucleus removed ...

  8. Moral Injury: The Grunts - The Huffington Post

    projects.huffingtonpost.com/moral-injury/the...

    Can we imagine ourselves back on that awful day in the summer of 2010, in the hot firefight that went on for nine hours? Men frenzied with exhaustion and reckless exuberance, eyes and throats burning from dust and smoke, in a battle that erupted after Taliban insurgents castrated a young boy in the village, knowing his family would summon nearby Marines for help and the Marines would come ...

  9. Protofection - Wikipedia

    en.wikipedia.org/wiki/Protofection

    One hypothesis for mitochondrial diseases is that mitochondrial damage and dysfunction play an important role in aging. Protofection is being researched as a possibly viable laboratory technique for constructing gene therapies for inherited mitochondrial diseases, such as Leber's hereditary optic neuropathy. Studies have shown that protofection ...