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  2. Tadalafil: Your Ultimate Guide to Dosages, Side Effects & More

    www.aol.com/tadalafil-ultimate-guide-dosages...

    Tadalafil is available in several dosages, from a minimum dosage of 2.5mg (milligrams) all the way up to a 20mg per tablet, the maximum dose of tadalafil in 24 hours. Tadalafil 10mg: Typical ...

  3. Cialis Side Effects: What to Expect (& How to Avoid Them) - AOL

    www.aol.com/cialis-side-effects-expect-avoid...

    Tadalafil side effects aren’t the only concern when taking this drug. As mentioned, Cialis can interact with other PDE5 inhibitors for ED, as well as medications prescribed to treat hypertension ...

  4. Your ED Pill Guide: Everything You Need to Know Before ... - AOL

    www.aol.com/ed-pill-guide-everything-know...

    Sildenafil (Viagra), tadalafil (Cialis) and vardenafil (Levitra) typically start working within 30 to 60 minutes, while avanafil (Stendra) works within 15 to 30 minutes. As with most prescription ...

  5. PDE5 inhibitor - Wikipedia

    en.wikipedia.org/wiki/PDE5_inhibitor

    Chemical structure of sildenafil (Viagra), the prototypical PDE5 inhibitor. A phosphodiesterase type 5 inhibitor (PDE5 inhibitor) is a vasodilating drug that works by blocking the degradative action of cGMP-specific phosphodiesterase type 5 (PDE5) on cyclic GMP in the smooth muscle cells lining the blood vessels supplying various tissues.

  6. Icos - Wikipedia

    en.wikipedia.org/wiki/Icos

    Icos is best known for the development of tadalafil (Cialis), a drug used to treat erectile dysfunction. This drug was discovered by GlaxoSmithKline, developed by Icos, and manufactured and marketed in partnership with Eli Lilly. Boosted by a unique advertising campaign led by the Grey Worldwide Agency, sales from Cialis allowed Icos to become ...

  7. Tadalafil - Wikipedia

    en.wikipedia.org/wiki/Tadalafil

    Tadalafil is not recommended in people taking nitrovasodilators such as nitroglycerin, as this may result in a serious drop in blood pressure. [8] Tadalafil is a PDE 5 inhibitor which increases blood flow to the penis. [8] It also dilates blood vessels in the lungs, which lowers the pulmonary artery pressure. [8]

  8. Is It Safe to Take Cialis Daily? - AOL

    www.aol.com/safe-cialis-daily-115900442.html

    Unlike other ED medications, such as Viagra® (sildenafil) and Levitra® (vardenafil), which work for four to five hours per dose, Cialis® (which contains the active ingredient tadalafil) is a ...

  9. Macitentan/tadalafil - Wikipedia

    en.wikipedia.org/wiki/Macitentan/tadalafil

    Macitentan/tadalafil, sold under the brand name Opsynvi, is a fixed dose combination medication used for the treatment of pulmonary arterial hypertension. [3] It contains macitentan , an endothelin receptor antagonist (ERA); and tadalafil , a phosphodiesterase 5 (PDE5) inhibitor .