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Iron overload (also known as haemochromatosis or hemochromatosis) is the abnormal and increased accumulation of total iron in the body, leading to organ damage. [1] The primary mechanism of organ damage is oxidative stress, as elevated intracellular iron levels increase free radical formation via the Fenton reaction.
[1] [4] In cases where high doses of elemental iron have been ingested and the patient is exhibiting signs and symptoms of severe systemic iron poisoning, supportive care measures like volume resuscitation and deferoxamine should be initiated immediately. [4] A quick response to iron poisoning can significantly improve clinical outcomes.
Haemochromatosis is protean in its manifestations, i.e., often presenting with signs or symptoms suggestive of other diagnoses that affect specific organ systems.Many of the signs and symptoms below are uncommon, and most patients with the hereditary form of haemochromatosis do not show any overt signs of disease nor do they have premature morbidity, if they are diagnosed early, but, more ...
The current flu season is shaping up to be a severe one for children. So far this season, 47 kids and teens have died from the flu, the Centers for Disease Control and Prevention reported Friday ...
Hemosiderin deposition in the liver is a common feature of hemochromatosis and is the cause of liver failure in the disease. Selective iron deposition in the beta cells of pancreatic islets leads to diabetes [4] [2] due to the distribution of transferrin receptor on the beta cells of islets [3] and in the skin leads to hyperpigmentation.
Reasonably effective ways to reduce the transmission of influenza include good personal health and hygiene habits such as: not touching your eyes, nose or mouth; [6] frequent hand washing (with soap and water, or with alcohol-based hand rubs); [6] eating a diet rich in fruits and vegetables; [16] covering coughs and sneezes; avoiding close contact with sick people; and staying home yourself if ...
As my body shed layers of skin, blood and thick mucus at an uncontrollable rate, they slathered layers of A&D cream, changed out fresh gauze, emptied the catheter drainage bag and cleaned out my ...
Vitamin and nutrient deficiencies can cause tooth decay, while bulimia can erode tooth enamel through excessive contact with stomach acid. Now, more than two weeks after the procedure, Macko’s ...
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related to: can high iron cause bruising on face home remedies for kids flu vaccine- 3579 S High St, Columbus, OH · Directions · (614) 409-0689