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Generalized pustular psoriasis (GPP) is a rare type of psoriasis that can present in a variety of forms. [1] Unlike the most general and common forms of psoriasis, GPP usually covers the entire body and with pus-filled blisters rather than plaques. GPP can present at any age, but is rarer in young children.
Acute GPP typically requires inpatient management including both topical and systemic therapy, and supportive measures. [3] Systemic glucocorticoid withdrawal is a common causative agent. [ 4 ] Withdrawal or administration of certain drugs in the patient's previous medication regimen may be required.
Generalized pustular psoriasis (GPP) is also known as (von Zumbusch) acute generalized pustular psoriasis in acute cases, and as impetigo herpetiformis during pregnancy. [3] [5] GPP is a rare and severe form of psoriasis that may require hospitalization. This form of psoriasis is characterized by an acute onset of numerous pustules on top of ...
The diagnosis of AGEP may be forthright in typical cases in which an individual: has taken a drug known to cause the disorder; develops multiple sterile pustules overlying large areas of red swollen skin starting a few days after initial drug intake; and has a histology of biopsied lesions that shows pustules just below the skin's Stratum ...
Pustule: A pustule is a small elevation of the skin usually consisting of necrotic inflammatory cells. [30] Cyst: A cyst is an epithelial-lined cavity. [10] Wheal: A wheal is a rounded or flat-topped, pale red papule or plaque that is characteristically evanescent, disappearing within 24 to 48 hours.
Papulopustular rosacea presents with some permanent redness with red bumps (papules); some pus-filled pustules can last 1–4 days or longer. This subtype is often confused with acne. Phymatous rosacea is most commonly associated with rhinophyma, an enlargement of the nose. Signs include thickening skin, irregular surface nodularities, and ...
Pustulosis is highly inflammatory skin condition resulting in large fluid-filled blister-like areas - pustules. Pustulosis typically occurs on the palms of the hands and/or the soles of the feet. The skin of these areas peels and flakes . [1]
Pustulosis palmaris et plantaris is a chronic recurrent pustular dermatosis (that is, a pustulosis or pustular psoriasis) localized on the palms and soles only, characterized histologically by intraepidermal pustules filled with neutrophils. [2]: 411, 628 [3]: 204 It can occur as part of the SAPHO syndrome. [4]