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The rate of cellular metabolic activity affects and, at the same time, is affected by the pH of the body fluids. In mammals, the normal pH of arterial blood lies between 7.35 and 7.50 depending on the species (e.g., healthy human-arterial blood pH varies between 7.35 and 7.45). [citation needed]
When an acid is dissolved in water, the pH will be less than 7, while a base, or alkali, will have a pH greater than 7. A strong acid, such as hydrochloric acid , at concentration 1 mol dm −3 has a pH of 0, while a strong alkali like sodium hydroxide , at the same concentration, has a pH of 14.
[13] [16] [17] [18] [1] The normal pH in the fetus differs from that in the adult. In the fetus, the pH in the umbilical vein pH is normally 7.25 to 7.45 and that in the umbilical artery is normally 7.18 to 7.38. [19] Aqueous buffer solutions will react with strong acids or strong bases by absorbing excess H + ions, or OH −
Acid–base imbalance is an abnormality of the human body's normal balance of acids and bases that causes the plasma pH to deviate out of the normal range (7.35 to 7.45). In the fetus, the normal range differs based on which umbilical vessel is sampled (umbilical vein pH is normally 7.25 to 7.45; umbilical artery pH is normally 7.18 to 7.38). [1]
In other words, water labeled “alkaline” doesn’t override your body’s natural ability to regulate pH. Your lungs and kidneys keep the pH of your blood tightly regulated between 7.35 to 7.45.
Lactic acidosis is commonly found in people who are unwell, such as those with severe heart and/or lung disease, a severe infection with sepsis, the systemic inflammatory response syndrome due to another cause, severe physical trauma, or severe depletion of body fluids. [3]
The tears are unique among body fluids in that they are exposed to the environment. Much like other body fluids, tear fluid is kept in a tight pH range using the bicarbonate buffer system. [15] The pH of tears shift throughout a waking day, rising "about 0.013 pH units/hour" until a prolonged closed-eye period causes the pH to fall again. [15]
Metabolic acidosis can lead to acidemia, which is defined as arterial blood pH that is lower than 7.35. [6] Acidemia and acidosis are not mutually exclusive – pH and hydrogen ion concentrations also depend on the coexistence of other acid-base disorders; therefore, pH levels in people with metabolic acidosis can range from low to high.