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It is estimated in 2018 there was an 85% for a survival rate of thirty years following a Fontan procedure and there are approximately 50,000 to 70,000 people in the world with Fontan circulation. [23] It is approximated that 40% of people with Fontan circulation are ≥18 years of age. [22]
Historically, during bypass surgeries, the heart is stopped and a heart-lung machine takes over the work of the heart and lungs. When a cardiac surgeon chooses to perform the CABG procedure off-pump (OPCAB) the heart is still beating while the graft attachments are made to bypass a blockage.
These patients typically require a Fontan procedure at 18 to 36 months of age following the Glenn BDG procedure. Examples of congenital cardiac malformations in which this procedure may be used include hypoplastic left heart syndrome, tricuspid atresia, double-inlet left ventricle and double-outlet right ventricle.
Arterial switch operation (ASO) or arterial switch, is an open heart surgical procedure used to correct dextro-transposition of the great arteries (d-TGA). [1] [2]Its development was pioneered by Canadian cardiac surgeon William Mustard and it was named for Brazilian cardiac surgeon Adib Jatene, who was the first to use it successfully.
Currently, infants undergo either the staged reconstructive surgery (Norwood or Sano procedure within a few days of birth, Glenn or Hemi-Fontan procedure at 3 to 6 months of age, and the Fontan procedure at 1 1/2 to 5 years of age) or cardiac transplantation. [10] Current expectations are that 70% of those with HLHS may reach adulthood. [18]
Long-term survival rates for children with single ventricle physiology are improving as medical and surgical advancements continue. In the major SVR trial (Single Ventricle Reconstruction) the transplant-free survival rate was only 54-59% amongst patients who underwent the Norwood procedure. [32]
Computational formula for the variance; ... Conditional expectation; ... Survival analysis; Survival rate; Survival function;
The graphs below show examples of hypothetical survival functions. The x-axis is time. The y-axis is the proportion of subjects surviving. The graphs show the probability that a subject will survive beyond time t. Four survival functions. For example, for survival function 1, the probability of surviving longer than t = 2 months is 0.37. That ...