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Children often have generalized lymphadenopathy of the head and neck, or even PGL, without the finding of a sinister cause. At puberty this usually disappears. The immune system of some people may be sensitized by exposure to a living exogenous irritant such as a bacterial or viral infection , which then results in PGL after the organism has ...
Chronic active Epstein–Barr virus infection (CAEBV) (also termed chronic active EBV infection of T and NK cells, systemic form) is a rare LPD [1] of children and, less often, adults. [25] CAEBV presents as severe, persistent form of infectious mononucleosis (IM) or a severe LPD disorder that follows months to years after a symptomatic (i.e ...
Localized lymphadenopathy: due to localized spot of infection; e.g., an infected spot on the scalp will cause lymph nodes in the neck on that same side to swell up; Inflammatory localized lymphadenopathy at right mandibular angle. Generalized lymphadenopathy: due to a systemic infection of the body; e.g., influenza or secondary syphilis
Generalized lymphadenopathy is swollen lymph glands in many areas of the body. [1]Usually this is in response to a body-wide infectious disease such as influenza and will go away once the person has recovered, but sometimes it can persist long-term, even when there is no obvious cause of disease.
It has been estimated that patients who present lymphadenopathy has an estimated 1.1% chance of developing malignancy. [11] The rate of childhood malignancy associated with lymphadenopathy is low, however this increases with age. A majority of reported cases in children are usually caused by infections or benign etiologies.
Kawasaki disease (also known as mucocutaneous lymph node syndrome) is a syndrome of unknown cause that results in a fever and mainly affects children under 5 years of age. [6] It is a form of vasculitis , in which medium-sized blood vessels become inflamed throughout the body. [ 1 ]
Lymph nodes may become enlarged in malignant disease. This cervical lymphadenopathy may be reactive or metastatic. [1] Alternatively, enlarged lymph nodes may represent a primary malignancy of the lymphatic system itself, such as lymphoma (both Hodgkin's and non-Hodgkin's), [6] lymphocytic leukemia, [1] Lymphadenopathy that lasts less than two weeks or more than one year with no progressive ...
Lymphedema, also known as lymphoedema and lymphatic edema, is a condition of localized swelling caused by a compromised lymphatic system. [2] The lymphatic system functions as a critical portion of the body's immune system and returns interstitial fluid to the bloodstream.