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The prevention of dementia involves reducing the number of risk factors for the development of dementia, and is a global health priority needing a global response. [1] [2] Initiatives include the establishment of the International Research Network on Dementia Prevention (IRNDP) [3] which aims to link researchers in this field globally, and the establishment of the Global Dementia Observatory ...
[14] [84] Smoking is a significant Alzheimer's disease risk factor. [1] Systemic markers of the innate immune system are risk factors for late-onset Alzheimer's disease. [85] Exposure to air pollution may be a contributing factor to the development of Alzheimer's disease. [14]
Non-genetic risk factors for early onset sporadic Alzheimer's disease and other forms of early onset dementia are understudied. However, recent research suggests that there are multiple modifiable and nonmodifiable risk factors for young onset dementia. [32]
The addition of vision loss and high cholesterol as risk factors comes as the number of people living with dementia around the world is expected to increase from 57 million in 2019 to 153 million ...
The studies that made the cut for this meta-analysis focused on the association between loneliness and all-cause dementia, as well as the risk for two specific types of dementia—Alzheimer’s ...
High cholesterol and vision loss are also newly identified risk factors for dementia. The authors say that LDL or "bad" cholesterol and vision loss were connected to 9% of dementia cases.
The neglect of these risk factors diminishes this reserve. [143] Sensory impairments of vision and hearing are modifiable risk factors for dementia. [144] These impairments may precede the cognitive symptoms of Alzheimer's disease for example, by many years. [145] Hearing loss may lead to social isolation which negatively affects cognition. [146]
The greatest risk factor for neurodegenerative diseases is aging. Mitochondrial DNA mutations as well as oxidative stress both contribute to aging. [ 54 ] Many of these diseases are late-onset, meaning there is some factor that changes as a person ages for each disease. [ 9 ]