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Tobacco smoking during pregnancy causes many detrimental effects on health and reproduction, in addition to the general health effects of tobacco.A number of studies have shown that tobacco use is a significant factor in miscarriages among pregnant smokers, and that it contributes to a number of other threats to the health of the foetus.
Smoking during pregnancy can cause adverse health effects in both the woman and the fetus. The 2008 US Guideline determined that "person-to-person psychosocial interventions" (typically including "intensive counseling") increased abstinence rates in pregnant women who smoke to 13.3%, compared with 7.6% in usual care.
In animal studies that resulted in birth defects, researchers found that nicotine negatively affects fetal brain development and pregnancy outcomes; [43] [41] the negative effects on early brain development are associated with abnormalities in brain metabolism and neurotransmitter system function. [120]
Nicotine itself could be at least partly responsible for many of the adverse after birth health results related to cigarette use while the mother was pregnant. [40] There is evidence that nicotine negatively affects fetal brain development and pregnancy outcomes. [42] There is also risk of stillbirth and pre-term birth. [43]
A National Institute on Drug Abuse video entitled Anyone Can Become Addicted to Drugs. [21]Nicotine dependence is defined as a neurobiological adaptation to repeated drug exposure that is manifested by highly controlled or compulsive use, the development of tolerance, experiencing withdrawal symptoms upon cessation including cravings, and an inability to quit despite harmful effects. [9]
The Health Survey for England in 2002 found a smoking rate of 26%. By 2007 the proportion of adult smokers in England had declined four percentage points to 22%. [47] In 2015, it was reported smoking rates in England had fallen to 16.9%, a record low. [48] The rate in England had fallen to 14.4% in 2018. [49]
Environmental toxicants and fetal development is the impact of different toxic substances from the environment on the development of the fetus.This article deals with potential adverse effects of environmental toxicants on the prenatal development of both the embryo or fetus, as well as pregnancy complications.
One of the most prominent and well studied epigenetic consequences of cigarette smoke is altered DNA methylation. Cigarette smoke acts through a number of mechanisms to effect this, chief among these being smoke-induced damage to the DNA and altered expression levels of proteins involved in DNA methylation and transcriptional regulation.