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  2. Exhaled nitric oxide - Wikipedia

    en.wikipedia.org/wiki/Exhaled_nitric_oxide

    Until the 1980s, nitric oxide, a product of fossil fuel combustion, was thought only to play a role the detrimental effects of air pollution on the respiratory tract. [17] In 1987, experiments with coronary arteries showed that nitric oxide was the long sought endothelium-derived relaxing factor.

  3. Nitrous oxide (medication) - Wikipedia

    en.wikipedia.org/wiki/Nitrous_oxide_(medication)

    Nitrous oxide, as medical gas supply, is an inhaled gas used as pain medication, and is typically administered with 50% oxygen mix. It is often used together with other medications for anesthesia . [ 2 ]

  4. Biological functions of nitric oxide - Wikipedia

    en.wikipedia.org/wiki/Biological_functions_of...

    Nitric oxide is absorbed systemically after inhalation. Most of it moves across the pulmonary capillary bed where it combines with hemoglobin that is 60% to 100% oxygen-saturated. Nitrate has been identified as the predominant nitric oxide metabolite excreted in the urine, accounting for >70% of the nitric oxide dose inhaled.

  5. Pulmonary drug delivery - Wikipedia

    en.wikipedia.org/wiki/Pulmonary_drug_delivery

    Pulmonary drug delivery is mainly utilized for topical applications in the lungs, such as the use of inhaled beta-agonists, corticosteroids and anticholinergic agents for the treatment of asthma and COPD, the use of inhaled mucolytics and antibiotics for the treatment of cystic fibrosis (CT) and respiratory viral infections, [1] and the use of inhaled prostacyclin analogs for the treatment of ...

  6. Dry-powder inhaler - Wikipedia

    en.wikipedia.org/wiki/Dry-powder_inhaler

    DPIs are an alternative to the aerosol-based inhalers commonly called metered-dose inhaler (or MDI). The DPIs may require some procedure to allow a measured dose of powder to be ready for the patient to take. The medication is commonly held either in a capsule for manual loading or in a proprietary form inside the inhaler.

  7. Nebulizer - Wikipedia

    en.wikipedia.org/wiki/Nebulizer

    In medicine, a nebulizer (American English) [1] or nebuliser (British English) [2] is a drug delivery device used to administer medication in the form of a mist inhaled into the lungs. Nebulizers are commonly used for the treatment of asthma , cystic fibrosis , COPD and other respiratory diseases or disorders.

  8. Acute Exposure Guideline Levels - Wikipedia

    en.wikipedia.org/wiki/Acute_Exposure_Guideline...

    Acute Exposure Guideline Levels (AEGLs) set levels of chemical concentration that pose a defined level of risk to humans (the general population, including susceptible individuals). [ 1 ] [ 2 ] [ 3 ] These levels are used in preventing and responding to disasters .

  9. Metered-dose inhaler - Wikipedia

    en.wikipedia.org/wiki/Metered-dose_inhaler

    MDI canister and actuator components from H&T Presspart. A metered-dose inhaler consists of three major components: the canister, which is produced in aluminum or stainless steel by means of deep drawing, where the formulation resides; the metering valve, which allows a metered quantity of the formulation to be dispensed with each actuation; and an actuator (or mouthpiece) which enables the ...

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