enow.com Web Search

Search results

  1. Results from the WOW.Com Content Network
  2. RNA editing - Wikipedia

    en.wikipedia.org/wiki/RNA_editing

    Base Editing: Base editing is the third major class of rRNA modification, specifically in eukaryotes. There are 8 categories of base edits that can occur at the gap between the small and large ribosomal subunits. [38] RNA methyltransferases are the enzymes that introduce base methylation. [38]

  3. RNA hydrolysis - Wikipedia

    en.wikipedia.org/wiki/RNA_hydrolysis

    RNA is susceptible to this base-catalyzed hydrolysis because the ribose sugar in RNA has a hydroxyl group at the 2’ position. [1] This feature makes RNA chemically unstable compared to DNA, which does not have this 2’ -OH group and thus is not susceptible to base-catalyzed hydrolysis. [1] Mechanism of base catalyzed RNA hydrolysis.

  4. Base excision repair - Wikipedia

    en.wikipedia.org/wiki/Base_excision_repair

    8-oxoguanine forms a Hoogsteen base pair with adenine. Single bases in DNA can be chemically damaged by a variety of mechanisms, the most common ones being deamination, oxidation, and alkylation. These modifications can affect the ability of the base to hydrogen-bond, resulting in incorrect base-pairing, and, as a consequence, mutations in the DNA.

  5. Post-transcriptional modification - Wikipedia

    en.wikipedia.org/wiki/Post-transcriptional...

    The pre-mRNA processing at the 3' end of the RNA molecule involves cleavage of its 3' end and then the addition of about 250 adenine residues to form a poly(A) tail.The cleavage and adenylation reactions occur primarily if a polyadenylation signal sequence (5'- AAUAAA-3') is located near the 3' end of the pre-mRNA molecule, which is followed by another sequence, which is usually (5'-CA-3') and ...

  6. Wobble base pair - Wikipedia

    en.wikipedia.org/wiki/Wobble_base_pair

    Wobble base pairs for inosine and guanine. A wobble base pair is a pairing between two nucleotides in RNA molecules that does not follow Watson-Crick base pair rules. [1] The four main wobble base pairs are guanine-uracil (G-U), hypoxanthine-uracil (I-U), hypoxanthine-adenine (I-A), and hypoxanthine-cytosine (I-C).

  7. DNA mismatch repair - Wikipedia

    en.wikipedia.org/wiki/DNA_mismatch_repair

    Examples of mismatched bases include a G/T or A/C pairing (see DNA repair). Mismatches are commonly due to tautomerization of bases during DNA replication. The damage is repaired by recognition of the deformity caused by the mismatch, determining the template and non-template strand, and excising the wrongly incorporated base and replacing it ...

  8. DNA glycosylase - Wikipedia

    en.wikipedia.org/wiki/DNA_glycosylase

    Base excision repair is the mechanism by which damaged bases in DNA are removed and replaced. DNA glycosylases catalyze the first step of this process. They remove the damaged nitrogenous base while leaving the sugar-phosphate backbone intact, creating an apurinic/apyrimidinic site, commonly referred to as an AP site.

  9. Transfer RNA - Wikipedia

    en.wikipedia.org/wiki/Transfer_RNA

    The modified base is often found within the sequence 5'-TΨCGA-3', with the T (ribothymidine, m5U) and A forming a base pair. [ 13 ] The variable loop or V loop sits between the anticodon loop and the ΨU loop and, as its name implies, varies in size from 3 to 21 bases.